Automatic Eye Drop Filling and Capping Machine

Automatic Eye Drop Filling and Capping Machine Model: LI-EFC 40, The machine consists of one Side turntables, S.S. slat conveyor belt, eccentric pre-gassing, filling & post–gassing S.S. -316 nozzles precision-built S.S. – 316 Syringes, silicon rubber tubings, pneumatic system for inner cap placement, mechanical orientation type bowl & chute for outer cap placement, easy – reach compact panel etc. Due to its minimum distance between filling and stoppering, the risk of contamination is reduced. It is designed for operating in a sterile area and for utilizing it under laminar flow protection. The un-scrambler itself has been designed in the machine to eliminate dead ends and difficult to clean spot.

Salient Features:

  • Filling, Inner Cap Placement & Screw Capping Unit is completely in corporate in single body Structure.
  • Pneumatic System for Inner Cap Placement
  • Mechanical Orientation type Bowl & Chute for Screw Cap Placement
  • All Liquid Contact Parts are of S.S. 316, the Body Structure is built up of S.S. 304 Pipe.
  • Co-eccentric Nozzles allows very quick and precise setting and making unit compact and manageable.
  • No vial, No Cap – Machine Stop System.
  • Easy reach compact panel provides ease and operation
  • Minimum Change over Time. From one size of container or fill size to another.
  • Each Important individual part required for autoclaving/ sterilization can be removed easily.

Technical Specification:

Model LI-EFC 40
Speed 40 to 60 Vials/ min.
Filling Volume 0.1 ml to 50 ml
Cap Diameter 20 mm, 25 mm & 28 mm
Filling Accuracy ±1 % on Single Dose
Power Characteristics 440v 3 Phase 50Hz 4 Wire System
Overall Dimension 900 x 900 x 1400 mm
Net Weight 550 Kilograms

Automatic Eye Drop Filling & Capping Machine (LI-EFC 40) FAQs


The LI-EFC 40 is a compact monoblock machine integrating filling, inner cap placement, and screw capping in a single sterile body — designed for ophthalmic solution manufacturing.

Filling, inner cap placement, and screw capping occur within one enclosed structure — minimizing open-container exposure and contamination risk.

The LI-EFC 40 operates at 40–120 bottles per minute depending on bottle size, fill volume, and formulation type.

Handles LDPE bottles (5–15 ml), glass eye drop bottles, and integrated nozzle-cap formats used in pharma and Ayurvedic ophthalmics.

Bottles move via SS slat conveyor to a star wheel indexing system for filling, inner cap placement, and torque-controlled screw capping.

Yes — SS 304 body, SS 316 contact parts, and sterile-zone compatibility ensure compliance with Schedule M, WHO-GMP, and USFDA norms.

Antibiotic, anti-inflammatory, antiglaucoma, antifungal, lubricating, mydriatic, and combination ophthalmic solutions.

Inert gas flushing before and after filling reduces oxygen exposure — protecting oxidation-sensitive formulations.

Minimizes sterile liquid exposure time — strengthening sterility assurance in ophthalmic filling.

Yes — designed for operation under LAF in sterile Grade A environments with minimal turbulence zones.

Automated pneumatic placement ensures contamination-free and consistent inner plug positioning.

A mechanical orientation bowl aligns caps before torque-controlled screw capping.

Yes — consistent filling accuracy, gas control, and sensor systems support full pharma validation protocols.

Sensors detect bottle presence, missing caps, fill errors, and automatically reject defective units.

Yes — compatible with open/closed RABS and isolator systems for enhanced sterility assurance.

Yes — supports sterile filling of Triphala, rose water, tulsi-based eye drops and other Ayurvedic solutions.

Yes — monoblock sterile design and SS 316 contact parts align with Schedule T and AYUSH GMP guidelines.

Yes — suitable for WHO-GMP, EU GMP Annex 1, USFDA, and international regulatory submissions.

Yes — its 40–120 BPM range supports pilot batches through full commercial production.

Yes — provides a long-term, validated sterile filling platform that scales with production demand.

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