Ampoule Filling & Sealing Machine


Glass Ampoule Filling & Sealing Equipment

The operation of filling and sealing the glass ampoules is achieved with ampoule filling and sealing machine. It largely finds application in industries like cosmetic, chemical, pharmaceutical, veterinary, and biotech industries.

Ampoule Filler Machine Manufacturing

At Lodha Pharma, with our state of the art manufacturing facilities, we design and manufacture ampoule filling & sealing machine adhering to preset manufacturing standards to ensure of finest quality. The machines developed are standard as well custom made models tailored to meet the desired application. During the operation, principal of slant movement of ampoules is used in order to incorporate a wide array of ampoules that differ in ovality, thickness, and neck dimensions.

Ampoule Filling & Sealing Machine Quality Assurance

With the frame structure of the ampoule filler being made from stainless steel square pipes, it provides an assurity of durability and hence high productivity. The frames have a matt finished design and also include stainless steel coverings that impart them an aesthetic appearance. Maintaining and cleaning of the machine turns out to be quite an easy task as the bottom portion of the machine has a big opening area.

To make sure that the machine operation is secure all the time, a pendant type electric control panel is provided in the machine that is raised to ease out the process.


Salient Features of Ampoule Filling Machine & Sealing Machine

  • Ampoule filling & sealing machine is a compact GMP model that provides assurance of its good workability
  • Output of the ampoule filling machine ranges from 30 ampoules to 150 ampoules per minute
  • AISI SS 316L is used in the construction of contact parts whereas, AISI SS 304 is utilized while manufacturing the non-contact parts
  • It is preferred for the application where ampoules having the fill capacity between 1-20 ml is used to be filled with the requisite contents. The ampoule machine does not require the parts to be changed for such operations
  • The “No Ampoule – No Filling” feature makes sure that the machine is not in an operating condition if there are no ampoules present
  • For the filling and gas flushing operations, the machine centers the ampoule neck for enhanced output
  • There is a chance of nitrogen gas to get flushed during the filling operation. Such behavior can also be expected to occur after or before filling
  • The ease of accessibility of this machine makes it very convenient to maintain
  • A pre-warming station is also provided in the machine
  • The ampoule filling and sealing machine requires the least change over time and is quite easy to clean

Ampoule Filling Machine Process

The operation of the machines starts with the sterilized ampoules being transferred to the hopper that is installed slantly. The transfer process of ampoules occur individually by the star wheel in an order manner on the ampoule rack that is eccentrically shaped having the capability of handling one/two/four/six ampoules.

Ampoule Sealing Machine Process

As the rack stops, pre-gassing, filling, post gassing, pre heating and sealing is performed in a sequential manner. These completely filled and sealed ampoules get transferred to the collection tray automatically without requiring any manual operation.


Ampoule Filler and Sealer Performs following operations

  • The in-feed hopper and star wheel attends the ampoule after which they are conveyed to the transport rack
  • In one machine stroke, two ampoules are transferred
  • The process of gas flushing, pre & post heating, and liquid filling involves the ampoule necks to get accurately centered
  • At pre-heating and heating station, ampoule neck is made to rotate
  • Any faulty ampoules having burdened-off tips are removed with the help of clippers and are collected in a different container

Advantages of Ampoule Filling Machine

Ampoule filler machine is extensively used by pharmaceutical companies for filling ampoules. It enables high production capacity to meet increasing demands. Companies can manufacture hundreds of ampules within short time with the help of ampoule filling machine. It is very easy to monitor ampoule filling process on ampule filling & sealing machine. Once the settings of ampule filler machine are completed, it can fill ampoules with the predefined amount of drugs. The biggest advantage of ampule filler machine is high accuracy. It ensure that exact amount of drug is filled in each ampule. As it is fully automatic, operating ampule filling and sealing machine is very easy.

Technical Specification of Ampoule Filling & Sealing Machine

Model LI-AFS 1 LI-AFS 2 LI-AFS 4 LI-AFS 6
No. of Head Single Two       Four Six
Ampoule Handling Range 1 ml to 20 ml 1 ml to 20 ml 1 ml to 10 ml 1 ml to 10 ml
Production Output 15 to 30 ampoules/minute 30 to 55 ampoules/minute 55 to 100 ampoules/minute 80 to 150 ampoules/minute
Filling Accuracy ± 1% ± 1% ± 1% ± 1%
Require Gas for Sealing LPG & Oxygen (O₂) LPG & Oxygen (O₂) LPG & Oxygen (O₂) LPG & Oxygen (O₂)
Nitrogen Flushing Pre & Post Nitrogen Flushing Available Pre & Post Nitrogen Flushing Available Pre & Post Nitrogen Flushing Available Pre & Post Nitrogen Flushing Available
Power Specification 0.5 H.P 1 H.P. 1 H.P. 1 H.P.
Electrical Characteristics 230 Volts, Single Phase, 50 Hertz, 4 Wire System 230 Volts, Single Phase, 50 Hertz, 4 Wire System 230 Volts, Single Phase, 50 Hertz, 4 Wire System 230 Volts, Single Phase, 50 Hertz, 4 Wire System
Contact Parts Made from Stainless Steel 316L Made from Stainless Steel 316L Made from Stainless Steel 316L Made from Stainless Steel 316L
Non Contact Parts Made from Stainless Steel 304 Made from Stainless Steel 304 Made from Stainless Steel 304 Made from Stainless Steel 304
Overall Dimension 915mm (L) x
610mm (W) x
965mm (H)
915mm (L) x
760mm (W) x
965mm (H)
1200mm (L) x
1070mm (W) x
965mm (H)
1600mm (L) x
1400mm (W) x
1400mm (H)
* Specification can be changed as per customers’ requirements
Automatic Ampoule Filling and Sealing Machine Video