Dry Heat Sterilizer

Dry Heat Sterilizer

Dry Heat Sterilizer

Sterilization by dry heat has become increasingly popular worldwide due to two main special factors first the need of sterilizing small objects, especially ampoules, syringes and secondly for de-pyrogenation of manufacturing apparatus which is impossible in a steam sterilizer. Dry heat sterilization and dehydrogenation process is mainly used for complete destruction and removal of all micro-organisms by means of dry heat. These stainless steel dry heat sterilizers use air as a medium of sterilization
Another advantage of this method of sterilization is that objects which are damaged by water or steam e.g. powder or ointment can be sterilized provided the heat penetrates to all parts of the substance.

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Applications:
  • Empty glassware (e.g. Vials, Ampoules and bottles).
  • Stainless steel and aluminium containers
  • Thermo stable basic pharmaceutical products and chemical compounds.
  • Non-aqueous liquid material (e.g. Oils, glycerine, etc.)
  • Powders like sulphonamides and talcum powder
  • Metal trays.

Salient Features:
  • Chamber is manufactured in SS316L. Fully welded with round corners.
  • The doors are of hinged type, equipped with double edge seal gasket for maximum safety
  • For operation, control and data acquisition a PLC is provided. HMI facilitates interface between operator and equipment.
  • Equipment’s are available with single door as well as double door pass through arrangement.
  • Bio seal flange to seal the equipment into the building wall can be provided
  • HEPA filters are installed in the fresh air, recirculation and exhaust module. In addition, 0.5 micron “Micro B” filter is installed as a pre-filter to the Fresh Air HEPA
  • Three modules for air handling
  • Fresh air (air intake)
  • Recirculation
  • Exhaust

Accessories

A complete range of carriages, transfer trolleys to simplify handling.
Plates, trays, wire baskets and other relevant accessories are supplied depending on the application

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Dry Heat Sterilizer FAQs

It uses high-temperature hot air (160°C–250°C) to destroy microorganisms by oxidation. Unlike steam autoclaves, it does not use moisture, making it ideal for glassware, metals, oils, and moisture-sensitive pharma materials.

It prevents corrosion, rust, and water stains while delivering sterile, completely dry equipment ready for aseptic use.

Depyrogenation destroys bacterial endotoxins. At 250°C for 30 minutes, it achieves validated endotoxin reduction required for injectable pharma manufacturing.

Yes — ideal for sterilizing glass containers, metal tools, and mineral-based formulations like Bhasmas.

They sterilize glass jars, metal components, spatulas, and heat-stable packaging before filling premium beauty products.

Common cycles: 160°C for 120 minutes, 170°C for 60 minutes, or 250°C for 30–45 minutes for sterilization plus depyrogenation.

Glass vials, ampoules, metal instruments, oils, waxes, mineral powders, and moisture-sensitive materials.

Yes — compliant with WHO-GMP, Schedule M, USP 1229.5, European Pharmacopoeia, and USFDA guidelines.

Static air relies on natural convection; forced air circulation ensures uniform temperature distribution required for validated pharma processes.

Through recirculating air fans, stainless steel baffles, calibrated heating elements, and validated temperature mapping.

Yes — mineral-based Ayurvedic formulations can undergo bioburden reduction in controlled high-temperature cycles.

IQ, OQ, PQ, temperature mapping, heat penetration studies, BI testing, and endotoxin challenge testing.

It depyrogenates glass vials and ampoules at 250°C before aseptic filling, ensuring endotoxin-free injectable packaging.

SS 316L chamber and shelves with mirror or electropolished finish for durability and GMP compliance.

Over-temperature protection, safety thermostats, alarms, HEPA filtration, and door interlock systems.

HEPA filters ensure particle-free hot air circulation, preventing recontamination before load removal.

Ensure adequate spacing, avoid overloading, and use foil wrapping where necessary to maintain sterility post-cycle.

Calibration every 6 months and full revalidation annually or after major repairs/parameter changes.

Modern units feature high-density insulation and PLC-controlled heating cycles for improved energy efficiency.

Selection depends on load type, depyrogenation needs, batch volume, regulatory requirements, and available space — consult a GMP-experienced manufacturer for correct specification.

What Our Clients Say About Us?

Our clients' feedback is always important for our growth.

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We’ve been using the Manual Capsule Filling Machine for several months and are very impressed with its performance. It's robust, easy to maintain, and ideal for our needs. Highly satisfied with Lodha International LLP.

The Automatic Capsule Loader from Lodha International revolutionizes the industry. It increased our production speed significantly while reducing human error. It is an excellent investment for any pharma company.

We’ve been using Lodha International LLP’s Ampoule Filling & Sealing Machine for a while, and it has exceeded our expectations. The machinery is highly effective in our filling processes.

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The pharmaceutical machinery from Lodha International LLP. has completely transformed our production line. Excellent performance and long-lasting quality—highly recommended!

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