R&D Lab Ampoule Filling and Sealing Machine

This ampoule filling and sealing machine is celebrated for its user-friendly operation, quality, and low maintenance needs. It includes automatic ampoule feeding, cleaning, filling, and sealing stations. The machine can handle up to 30 ampoules per minute, making it an important tool in the pharmaceutical, biotechnology, cosmetic, veterinary, and chemical industries. We offer both standard and custom models of our R&D ampoule filling machine to meet specific customer requirements.

As a top ampoule filling and sealing machine manufacturer, Lodha International LLP takes pride in producing high-quality equipment. Our machines are designed for easy operation and dependable performance. This high-speed ampoule filling and sealing machine is ideal for R&D labs needing precise and efficient ampoule processing. As a trusted ampoule filling and sealing machine exporter, we deliver our advanced machinery worldwide, that meets the various needs of our global clients.

Salient Features of R&D Lab Ampoule Filling and Sealing Machine:


  • Compact design compliant with GMP standards
  • Contact parts are made of AISI SS 316L, while non-contact parts are made of AISI SS 304
  • Minimal changeover parts needed for ampoule sizes from 1 ml to 10 ml
  • Equipped with a "No Ampoule — No Filling" system
  • Makes sure ampoule neck centering during gas flushing and filling
  • Allows nitrogen gas flushing before, during, and after filling
  • Easy access for maintenance
  • Includes a pre-warming station
  • Quick changeover times, low maintenance requirements, and easy cleaning

Process Operation of R&D Lab Ampoule Filling and Sealing Machine


Sterilized ampoule trays are loaded directly into the unit's slant hopper. A synchronized star wheel delivers the ampoules one by one onto a moving eccentric ampoule rack in groups of four. During the rack's stoppage, pre-gassing, filling, post-gassing, pre-heating, and final sealing occur sequentially. The filled and sealed ampoules are then automatically collected on a collection tray without any manual handling. This streamlined process confirms high efficiency and consistency, making the R&D lab ampoule filling and sealing machine an invaluable asset for laboratories and production facilities. The automatic functions and strong construction of the machine deliver reliable performance and easy integration into various industrial applications.


Technical Specification of R&D Lab Ampoule Filling and Sealing Machine:


Model: LI – AFS 1L
NO. of Head Single
Ampoule Handling Range 1ml to 20ml
Production Output 15 to 30 ampoules/minute
Filling Accuracy ± 1%
Require Gas for Sealing LPG & Oxygen (O₂)
Nitrogen Flushing Pre & Post Nitrogen Flushing Available
Power Specification 0.5 H.P.
Electrical Characteristics 230 Volts, Single Phase, 50 Hertz, 4 Wire System
Contact Parts Made from Stainless Steel 316L
Non-Contact Parts Made from Stainless Steel 304
Overall Dimension 915mm (L) x 61 Omm (W) x 965mm (H)
* Power voltage can be adjusted as per customer's domestic power voltage requirements.
* Rights of technical improvements & modification reserved.
* Illustrations & dimensions are shown for information purpose only.

R&D Lab Ampoule Filling & Sealing Machine – FAQs


A compact bench-top machine designed to accurately fill and flame-seal glass ampoules for pharmaceutical, Ayurvedic, and cosmetic product development, stability batches, and regulatory samples.

It fills ampoules using a calibrated pump system and then hermetically seals them using an oxy-gas flame sealing mechanism within seconds.

Aqueous injections, oil-based formulations, herbal extracts, ophthalmic solutions, cosmetic serums, and diagnostic liquids.

It allows Ayurvedic manufacturers to produce sealed stability and regulatory submission batches before investing in commercial-scale lines.

For developing premium single-dose cosmetic ampoules used in stability testing, sampling, and product launches.

Standard glass ampoules from 1 ml to 30 ml with ±1% filling accuracy.

Yes — typically 10–30 ampoules per minute, suitable for ICH stability batches and clinical samples.

Ceramic piston pumps for accuracy and solvent compatibility, or peristaltic pumps for biological and shear-sensitive liquids.

A focused oxy-gas flame melts the ampoule neck, forming a smooth, hermetic seal.

Yes — nitrogen purging protects oxygen-sensitive pharma and cosmetic formulations during filling.

SS 316L product-contact parts, calibrated filling system, documented sealing parameters, and compatibility with aseptic environments.

Yes — compact footprint allows placement inside laminar airflow workstations for aseptic filling.

SS 316L, borosilicate glass, PTFE tubing — ensuring chemical compatibility and GMP compliance.

It produces consistent, hermetically sealed ampoules required for long-term stability and regulatory submissions.

Flushing, disassembly, WFI rinsing, drying, and documented cleaning SOP compliance between batches.

Yes — with ceramic piston pump and optional heating for viscous oil-based preparations.

Enables rapid development of premium single-dose ampoule cosmetic products for sampling and launch.

Installation, operator training, calibration services, spare parts, and technical support.

Yes — when operated under aseptic conditions with documented accuracy and sealing validation.

Consider ampoule size range, formulation type, nitrogen purging needs, accuracy, throughput, and supplier support.

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