R&D High Shear Mixer Granulator Machine

Lodha International LLP is the leading manufacturer of the R&D high shear mixer granulator machine. This machine delivers accurate, quick, and consistent granulation, suitable for both water and solvent granulation processes. The granulator maintains a steady agitated state to prevent lumps in the product. Constructed to GMP standards, the machine features a strong frame and base made from AISI 304 stainless steel, reducing noise and vibrations. All product-contacting components are designed from mirror-polished AISI 316L stainless steel. The bowl's silicone gasket is a single, removable piece for easy cleaning, and a pneumatic actuator operates the lid. The machine includes a slow-moving mixing blade and a fast-moving granulation chopper, both equipped with pneumatic seals on their shafts.

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This high shear mixer granulator improves tablet hardness and solubility while reducing the need for binder agents by up to 70% compared to other granulators. The lab rapid mixer granulator is designed to meet specific tablet production requirements, offering superior mixing and uniform granules at reduced operating costs. The granulator supports increased tableting speeds without compromising quality, making it an important tool for various industries, including pharmaceuticals, chemicals, cosmetics, food, and general mixing. Lodha International LLP provides advanced rapid mixer granulator R&D lab models that deliver precise and efficient mixing for high-quality production.

Salient Features of R&D High Shear Mixer Granulator Machine:

It makes sure that the binder is evenly distributed throughout the mixture
Users can adjust the speed of the mixer and chopper blades as needed
It can handle both water-based and solvent-based processing
It has a quick batch time and is easy to clean, saving time and effort
It maximizes the effectiveness of the cleaning-in-place (CIP) process
The machine has an air purge sealing system to prevent contamination
An optional jacketed bowl allows for control of the product's temperature
All parts that come into contact with the product are polished for cleanliness
It comes with interchangeable product bowls in various sizes
The machine is a self-contained system with a bottom drive

Process Operation of R&D High Shear Mixer Granulator Machine

The machine operates by agitating the materials in the bowl at a moderate speed, followed by the high-speed action of a specially designed cutter blade on the wet mass. The processing time varies based on the number of ingredients and their particle sizes. Optional features include a product temperature probe and a heating jacket with a vacuum system for drying processes. This operation method offers precise control over mixing and granulation, making the high shear mixer granulator an important asset for labs and production facilities. Its advanced design and strong features enable efficient and hygienic granulation, supporting various industrial applications.

Technical Specification of R&D High Shear Mixer Granulator Machine:

Technical Specification	Lab Models			Interchangeable Model
Technical Specification	LI-RMG 3	LI-RMG 5	LI-RMG 10	LI-RMG INTR
Working Capacity in Litres	3	5	10	2.5/7.5/12
Working Capacity in Kilograms	0.5 to 1.2	1 to 2	2 to 4	1 / 3 / 5
Main Motor 750/1440 RPM	2/3	2/3	2/3	2/3
Chopper Motor 1440/2880 RPM	0.5/1	0.5/1	0.5/1	0.5/1
Gear Box Size	NMRV P075	NMRV P075	NMRV P075	NMRV P075

R&D High Shear Mixer Granulator – FAQs

A compact wet granulation system using a high-speed impeller and chopper blade to mix and granulate powders in a single closed bowl — essential for reproducible pharma and Ayurvedic solid dosage development.

The impeller mixes powders while binder liquid is sprayed in, and the chopper controls agglomerate size — producing dense, uniform granules with excellent flow and compressibility.

Immediate-release, modified-release, effervescent, dispersible tablets, and potent API granulations requiring improved flow and uniformity.

It enables reproducible granule development for Churna-based tablets, herbal extract granules, and effervescent Ayurvedic formulations.

It develops uniform granulations for pressed powders, bath tablets, and compact cosmetics requiring controlled density and particle size.

From 1–3L bench models to 5–25L pilot scale and 50–150L tech transfer units with geometric similarity for scale-up.

Impeller speed, chopper speed, liquid addition rate, mixing time, temperature, and torque-based end-point detection.

It generates DoE data on binder rate, speed, and granulation end-point — forming the pharmaceutical development section of regulatory dossiers.

Torque monitoring, power consumption tracking, motor current analysis, and optional NIR spectroscopy integration.

By defining proven acceptable ranges (PAR) for process variables that transfer directly to production-scale granulators.

SS 316L electropolished product-contact surfaces meeting WHO-GMP, Schedule M, and AYUSH GMP standards.

It produces documented, reproducible granulation data supporting AYUSH Form 24/24A product dossiers.

Documented cleaning SOPs, swab testing, validated cleaning agents, and residual API verification.

Yes — closed bowl design and optional negative pressure containment reduce operator exposure risks.

It breaks oversized wet agglomerates and controls upper particle size distribution for uniform granules.

High shear produces denser granules ideal for compression, while fluid bed creates lighter, porous granules.

It ensures uniform pigment distribution and optimal density for pressed cosmetic compacts.

In-line NIR spectroscopy, torque monitoring, FBRM particle tracking, and temperature probes.

Installation, process training, spare parts, calibration services, and granulation troubleshooting support.

Select based on batch size, API potency, scale-up similarity, PAT needs, cleaning validation, GMP framework, and supplier expertise.

What Our Clients Say About Us?

Our clients' feedback is always important for our growth.

We've been using the Manual Capsule Filling Machine from Lodha International LLP for months now. It's efficient and easy to operate. Great value for the investment!

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We’ve been using the Manual Capsule Filling Machine for several months and are very impressed with its performance. It's robust, easy to maintain, and ideal for our needs. Highly satisfied with Lodha International LLP.

The Automatic Capsule Loader from Lodha International revolutionizes the industry. It increased our production speed significantly while reducing human error. It is an excellent investment for any pharma company.

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The pharmaceutical machinery from Lodha International LLP. has completely transformed our production line. Excellent performance and long-lasting quality—highly recommended!

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R&D High Shear Mixer Granulator Machine