Automatic Ampoule Filler Sealer

Automatic Ampoule Filler Sealer

Automatic Ampoule Filler Sealer

Automatic Ampoule Filler Sealer Model: LI-AFS is used for filling and sealing of glass ampoules. Machine is widely uses in pharmaceutical, biotech, cosmetic, veterinary & chemical industry. We design Ampoule Filling and Sealing Machine as per our standard model as well as custom made models according to customer’s specific requirements.
Machine built on principal of slant travel of ampoules while filling and sealing to take care wide variation of ampoule neck dimensions, thicknesses and ovality of available ampoules.
Ampoule Filling and Sealing Machine is built on Stainless Steel square pipes frame & totally encompassed with Stainless Steel coverings in pleasing matt finish design. Large opening area configured on bottom side of the machine for absolute cleaning and maintenance of the machine.
The pendant type electrical control panel is lifted from machine for ease of operation and safety

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Salient Features of Automatic Ampoule Filler Sealer

  • Compact GMP model
  • Production output ranging from 30 ampoules/minute to 150 ampoules/minute
  • All contact parts made from AISI SS 316L & other Non-contact parts made from AISI SS 304.
  • Machine is suitable to fill 1ml to 20ml ampoules and minimum change over parts from 1ml to 20ml ampoule size
  • “No Ampoule – No Filling” system
  • Ampoule neck centering during gas flushing and filling operations
  • Possibility of nitrogen gas flushing before, during and after filling
  • Full accessibility allows easy maintenance
  • Machine equipped with pre-warming station
  • Minimum change over time, little maintenance & easy cleaning

Process Operation of Automatic Ampoule Filler Sealer

The sterilized ampoule tray directly loaded in to slant hopper of the unit. The Synchronized star wheel delivers ampoules one by one on moving eccentric ampoule rack in single/two/four/six.
During the stoppage of rack sequentially pre-gassing, filling, post gassing, pre heating and final sealing is achieved. Duly filled sealed ampoules then collected on collection tray automatically without hand touch.

Automatic Ampoule Filler Sealer machine performs the following operations

  • Ampoule feeding by in-feed hopper, star wheel and ampoules transfer into transport rack.
  • Two ampoules advanced per machine stroke.
  • Centering of ampoules necks during pre-heating, post heating, gas flushing and liquid filling.
  • Rotation of ampoules neck in the pre- heating and heating station.
  • Elimination of burdened-off ampoule tips by clippers and ejection into a separate container.

Technical Specifications of Automatic Ampoule Filler Sealer

Model LI-AFS 4 LI-AFS 6
No. of Head Four Six
Ampoule Handling Range 1 ml to 10 ml 1 ml to 10 ml
Production Output 55 to 100 ampoules/minute 80 to 150 ampoules/minute
Filling Accuracy ± 1% ± 1%
Require Gas for Sealing LPG & Oxygen (O₂) LPG & Oxygen (O₂)
Nitrogen Flushing Pre-& Post Nitrogen Flushing Available Pre & Post Nitrogen Flushing Available
Power Specification 1 H.P. 1 H.P.
Electrical Characteristics 230 Volts, Single Phase, 50 Hertz, 4 Wire System 230 Volts, Single Phase, 50 Hertz, 4 Wire System
Contact Parts Made from Stainless Steel 316L Made from Stainless Steel 316L
Non-Contact Parts Made from Stainless Steel 304 Made from Stainless Steel 304
Overall Dimension 1200mm (L) x 1070mm (W) x 965mm (H) 1600mm (L) x 1400mm (W) x 1400mm (H)
* Specification can be changed as per customers’ requirements

Automatic Ampoule Filler Sealer Video

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Faq's

The Automatic Ampoule Filler Sealer is designed for the precise filling and sealing of ampoules in a single process and is widely used in the pharmaceutical industry to handle liquid drugs that require sterile conditions Lodha Pharma — combining two critical production steps in one compact, fully automated machine to eliminate contamination risk and maximize production efficiency.

The Automatic Ampoule Filler Sealer Model LI-AFS is widely used in pharmaceutical, biotech, cosmetic, veterinary, and chemical industries Lodha Pharma — making it a highly versatile machine for pharma injectable manufacturers, Ayurvedic sterile liquid producers, and cosmetic ampoule brands across India and global markets.

The machine is suitable to fill 1ml to 20ml ampoules with minimum change over parts from 1ml to 20ml ampoule size Lodha Pharma — giving pharma, Ayurvedic, and cosmetic manufacturers the flexibility to run multiple ampoule formats on the same machine with minimal downtime between size changeovers.

The machine is built on the principle of slant travel of ampoules while filling and sealing to take care of wide variation of ampoule neck dimensions, thicknesses, and ovality of available ampoules Lodha Pharma — ensuring reliable, jam-free processing of real-world ampoules that vary slightly in shape and neck dimensions from batch to batch.

The machine offers the possibility of nitrogen gas flushing before, during, and after filling Lodha Pharma — a critical feature for pharma injectables, Ayurvedic sterile liquid formulations, and cosmetic ampoules containing oxidation-sensitive actives that require an inert atmosphere to preserve potency and shelf life.

The machine is equipped with a "No Ampoule – No Filling" system Lodha Pharma — automatically halting the fill cycle whenever an ampoule is absent in the transport rack, preventing costly liquid wastage, nozzle contamination, and downtime caused by uncontrolled spillage on your pharma or cosmetic production line.

All contact parts are made from high quality Stainless Steel 316L and other non-contact parts are made from Stainless Steel 304 Lodha Pharma — meeting the highest cGMP, WHO-GMP, and US FDA material standards required for sterile pharmaceutical injectables, Ayurvedic sterile preparations, and regulated cosmetic ampoule products.

During the stoppage of the rack, sequentially pre-gassing, filling, post gassing, pre-heating, and final sealing is achieved — duly filled and sealed ampoules are then collected on the collection tray automatically without hand touch Lodha Pharma — ensuring a fully automated, contamination-free sealing process that maintains the sterility and medicinal integrity of every ampoule.

The sterilized ampoule tray is directly loaded into the slant hopper of the unit — the synchronized star wheel delivers ampoules one by one on the moving eccentric ampoule rack — and duly filled and sealed ampoules are collected on the collection tray automatically without hand touch Lodha Pharma — minimizing operator contact and maintaining sterility throughout the entire production cycle.

The machine is versatile and suitable for a variety of liquid products, including those used in cosmetics and pharmaceuticals Lodha Pharma — making it an excellent choice for cosmetic brands filling premium vitamin C ampoules, hyaluronic acid serum vials, anti-aging actives, and other high-value cosmetic liquid preparations in sealed glass ampoules.

The Automatic Ampoule Filler Sealer is capable of filling and sealing thousands of ampoules per hour Lodha Pharma — with exact output depending on ampoule size, fill volume, and number of filling heads configured — making it suitable for both mid-scale Ayurvedic manufacturers and large-volume pharma injectable production facilities.

The frame structure of the ampoule filler is made from stainless steel square pipes, providing an assurance of durability and high productivity — the frames have a matt finished design and also include stainless steel coverings that impart an aesthetic appearance Lodhapharma — while also meeting the cGMP construction standards required in sterile pharma and Ayurvedic manufacturing environments.

Maintaining and cleaning of the machine turns out to be quite easy as the bottom portion of the machine has a big opening area Lodhapharma — and with full accessibility allowing easy maintenance Lodha Pharma, the machine is designed to minimize cleaning downtime between product batches — critical for pharma and cosmetic manufacturers running multiple ampoule formulations.

The machine can use either oxygen or LPG (propane) gas for sealing and filling, making it suitable for different chemicals such as agro-insecticides, veterinary pharmaceuticals, and cosmetic ampoules Lodha Pharma — giving manufacturers across pharma, Ayurvedic, and cosmetic industries the flexibility to use the most appropriate gas combination for their specific product and ampoule type.

The Ampoule Filling and Sealing Machine with Servo based system has been designed and built in compliance with cGMP standards — it is equipped with PLC and HMI based control panel for auto fill volume adjustments and has a wide range of uses in pharmaceutical, biotech, cosmetic, veterinary, and chemical industry Lodha Pharma — offering superior precision and recipe-based control compared to conventional mechanical models.

The elimination of burnt-off ampoule tips is done by clippers and ejected into a separate container Lodha Pharma — this automatic tip removal system ensures that no broken glass fragments contaminate the sealed ampoule batch, maintaining product safety and regulatory compliance for pharma and cosmetic manufacturers.

Absolutely. The machine's sterile filling environment, nitrogen gas flushing capability, SS 316L contact parts, and no-hand-touch automated collection system make it fully suitable for Ayurvedic manufacturers producing sterile formulations — including herbal eye drops, plant-based injectables, and other Ayurvedic sterile liquids that demand contamination-free ampoule packaging.

Lodha Pharma designs Ampoule Filling and Sealing Machines as per their standard model as well as custom made models according to customer's specific requirements Lodha Pharma — meaning pharma companies, Ayurvedic manufacturers, and cosmetic brands can request tailored configurations for head count, ampoule size range, fill volume, sealing type, and conveyor integration to match their exact facility and product needs.

LODHA International LLP is committed to providing high-quality, efficient, and reliable Ampoule Filling and Sealing Machines that cater to the needs of various industries — their range of products is designed to improve production efficiency while maintaining the highest standards of quality and sterility Lodha Pharma — backed by decades of manufacturing experience and a global installed base across pharma, Ayurvedic, and cosmetic sectors.

Reach out to Lodha International LLP with your product details, bottle specifications, and target output — and their technical sales team will provide a tailored recommendation and quotation.
📞 +91 9687731331 | +91 9687631331 | +91 9537131331
📧 info@lodhapharma.com
🌐 www.lodhapharma.com
With 15,500+ machines installed across 50+ countries since 1995, Lodha International LLP is one of India's most trusted pharmaceutical, Ayurvedic, and cosmetic packaging machinery manufacturers.

What Our Clients Say About Us?

Our clients' feedback is always important for our growth.

We've been using the Manual Capsule Filling Machine from Lodha International LLP for months now. It's efficient and easy to operate. Great value for the investment!

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We’ve been using the Manual Capsule Filling Machine for several months and are very impressed with its performance. It's robust, easy to maintain, and ideal for our needs. Highly satisfied with Lodha International LLP.

The Automatic Capsule Loader from Lodha International revolutionizes the industry. It increased our production speed significantly while reducing human error. It is an excellent investment for any pharma company.

We’ve been using Lodha International LLP’s Ampoule Filling & Sealing Machine for a while, and it has exceeded our expectations. The machinery is highly effective in our filling processes.

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