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Onion Skin Ampoule Filling Machine

Onion Skin Ampoule Filling Machine

Onion Skin Ampoule Filling Machine Manufacturer

Onion Skin Ampoule Filling Machine Model: LI-OFS, is used for filling and sealing of glass ampoules. Machine is widely uses in pharmaceutical, biotech, cosmetic, veterinary & chemical industry. We design Ampoule Filling and Sealing Machine as per our standard model as well as custom made models according to customer’s specific requirements.
Machine built on principal of slant travel of ampoules while filling and sealing to take care wide variation of ampoule neck dimensions, thicknesses and ovality of available ampoules.
Ampoule Filling and Sealing Machine is built on Stainless Steel square pipes frame & totally encompassed with Stainless Steel coverings in pleasing matt finish design. Large opening area configured on bottom side of the machine for absolute cleaning and maintenance of the machine.
The pendant type electrical control panel is lifted from machine for ease of operation and safety

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Onion Skin Ampoule Filling Machine Salient Features

  • Compact GMP model
  • Production output ranging from 30 ampoules/min. to 150 ampoules/min.
  • All contact parts made from AISI SS 316L & other Non-contact parts made from AISI SS 304.
  • Machine is suitable to fill 1ml to 20ml ampoules and minimum change over parts from 1ml to 20ml ampoule size
  • “No Ampoule – No Filling” system
  • Ampoule neck centering during gas flushing and filling operations
  • Possibility of nitrogen gas flushing before, during and after filling
  • Full accessibility allows easy maintenance
  • Machine equipped with pre-warming station
  • Minimum change over time, little maintenance & easy cleaning

Onion Skin Ampoule Filling Machine Process Operation

The sterilized ampoule tray directly loaded in to slant hopper of the unit. The Synchronized star wheel delivers ampoules one by one on moving eccentric ampoule rack in single/two/four/six.
During the stoppage of rack sequentially pre-gassing, filling, post gassing, pre heating and final sealing is achieved. Duly filled sealed ampoules then collected on collection tray automatically without hand touch.

The machine performs the following operations

  • Ampoule feeding by in-feed hopper, star wheel and ampoules transfer into transport rack.
  • Two ampoules advanced per machine stroke.
  • Centering of ampoules necks during pre-heating, post heating, gas flushing and liquid filling.
  • Rotation of ampoules neck in the pre- heating and heating station.
  • Elimination of burdened-off ampoule tips by clippers and ejection into a separate container.

Technical Specification of Onion Skin Ampoule Filling Machine

Model LI-OAFS 1 LI-OAFS 2 LI-OAFS 4 LI-OAFS 6
No. of Head Single Two Four Six
Ampoule Handling Range 1 ml to 20 ml 1 ml to 20 ml 1 ml to 10 ml 1 ml to 10 ml
Production Output 15 to 30 ampoules/minute 30 to 55 ampoules/minute 55 to 100 ampoules/minute 80 to 150 ampoules/minute
Filling Accuracy ± 1% ± 1% ± 1% ± 1%
Require Gas for Sealing LPG & Oxygen (O₂) LPG & Oxygen (O₂) LPG & Oxygen (O₂) LPG & Oxygen (O₂)
Nitrogen Flushing Pre-& Post Nitrogen Flushing Available Pre-& Post Nitrogen Flushing Available Pre-& Post Nitrogen Flushing Available Pre-& Post Nitrogen Flushing Available
Power Specification 0.5 H. P 1 H.P. 1 H.P. 1 H.P.
Electrical Characteristics 230 Volts, Single Phase, 50 Hertz, 4 Wire System 230 Volts, Single Phase, 50 Hertz, 4 Wire System 230 Volts, Single Phase, 50 Hertz, 4 Wire System 230 Volts, Single Phase, 50 Hertz, 4 Wire System
Contact Parts Made from Stainless Steel 316L Made from Stainless Steel 316L Made from Stainless Steel 316L Made from Stainless Steel 316L
Non-Contact Parts Made from Stainless Steel 304 Made from Stainless Steel 304 Made from Stainless Steel 304 Made from Stainless Steel 304
Overall Dimension 915mm (L) x
610mm (W) x
965mm (H)		 915mm (L) x
760mm (W) x
965mm (H)		 1200mm (L) x
1070mm (W) x
965mm (H)		 1600mm (L) x
1400mm (W) x
1400mm (H)
* Specification can be changed as per customers’ requirements

Industries Using Onion Skin Ampoule Filling Machine

  • Pharmaceutical Industry Sterile injectable filling and hermetic sealing of glass ampoules.
  • Vaccine Industry Single-dose vaccine and biological filling.
  • Biopharmaceutical Industry Biologicals and high-value formulations in small volumes.
  • Ayurvedic Industry Herbal injectables and ark preparations in sealed ampoules.
  • Cosmetic Industry Ampoule-based serums and single-dose skincare.
  • Laboratories & Research Centers Pilot batches and stability-study filling.

Onion Skin Ampoule Filling Machine FAQs

The Onion Skin Ampoule Filler Sealer is designed for ampoules that have an "onion skin" finish at the top — it is used for filling and sealing of glass ampoules and is particularly useful for certain pharmaceutical and cosmetic applications where a specific type of sealing is required Lodha Pharma — making it the specialized solution for pharma, Ayurvedic, and cosmetic manufacturers whose product packaging demands the distinct layered onion skin tip closure rather than a standard pulled or cut seal.

The Onion Skin Ampoule Filler Sealer is designed to create the "onion skin" finish on ampoules, which is required for specific applications Lodha Pharma — this distinctive layered tip finish provides a clean, smooth breakpoint that allows easy and safe ampoule opening without glass splintering — a critical requirement for injectable pharma products, Ayurvedic sterile preparations, and cosmetic ampoules where patient and user safety during opening is a primary concern.

The Onion Skin Ampoule Filling Machine Model LI-OFS is used for filling and sealing of glass ampoules and is widely used in pharmaceutical, biotech, cosmetic, veterinary, and chemical industries Lodha Pharma — making it a highly versatile specialized filling solution that serves pharma injectable manufacturers, Ayurvedic sterile liquid producers, cosmetic ampoule brands, and veterinary drug companies across India and international export markets.

The Onion Skin Ampoule Filler Sealer boasts a production rate of 90 tubes per minute and is a boon to manufacturers of pharmaceuticals, cosmetics, cosmeceuticals, and the likes Lodha Pharma — delivering reliable high-speed throughput that keeps pace with demanding pharma injectable, Ayurvedic sterile liquid, and cosmetic ampoule production line requirements without compromising on seal quality or fill accuracy.

The machine is suitable to fill 1ml to 20ml ampoules with minimum change over parts from 1ml to 20ml ampoule size Lodha Pharma — giving pharma, Ayurvedic, and cosmetic manufacturers the flexibility to run the full range of ampoule formats on the same machine with fast, tool-friendly size changeovers and minimal production downtime between different product batches.

The machine is built on the principle of slant travel of ampoules while filling and sealing to take care of wide variation of ampoule neck dimensions, thicknesses, and ovality of available ampoules Lodha Pharma — ensuring jam-free, reliable processing of real-world ampoule batches that inevitably have slight dimensional variations in neck size, wall thickness, or shape — preventing costly production stoppages at high operating speeds.

The sterilized ampoule tray is directly loaded into the slant hopper of the unit — the synchronized star wheel delivers ampoules one by one on the moving eccentric ampoule rack in single, two, four, or six — during the stoppage of the rack, sequentially pre-gassing, filling, post gassing, pre-heating, and final sealing is achieved — and duly filled and sealed ampoules are then collected on the collection tray automatically without hand touch Lodha Pharma — ensuring a completely hands-free, contamination-free production cycle from ampoule feeding through to final collection.

Centering of ampoule necks during pre-heating, post heating, gas flushing, and liquid filling — rotation of ampoule necks in the pre-heating and heating station Lodha Pharma — ensures that every ampoule is perfectly positioned and rotated during each critical stage of the onion skin filling and sealing process, delivering the consistent, uniform layered tip finish that defines the onion skin seal on every single ampoule produced.

Elimination of burned-off ampoule tips is done by clippers and ejected into a separate container Lodha Pharma — this automatic tip removal and ejection system ensures that no glass fragments or burnt tip debris contaminate the sealed ampoule batch, maintaining complete product safety and regulatory compliance for pharma injectable, Ayurvedic sterile preparation, and cosmetic ampoule production.

All contact parts are made from AISI SS 316L and other non-contact parts are made from AISI SS 304 Lodhapharma — the highest pharmaceutical-grade stainless steel grades — ensuring zero contamination risk, full corrosion resistance, easy autoclaving between batches, and complete compliance with cGMP, WHO-GMP, and US FDA material standards for sterile pharma injectables, Ayurvedic sterile preparations, and premium cosmetic ampoule products.

The Ampoule Filling and Sealing Machine is built on Stainless Steel square pipe frame and totally encompassed with Stainless Steel coverings in pleasing matt finish design — with a large opening area configured on the bottom side of the machine for absolute cleaning and maintenance Lodha Pharma — delivering a robust, hygienic, cGMP-compliant structure that is visually clean, audit-ready, and fully compatible with regulated clean room environments in pharma, Ayurvedic, and cosmetic manufacturing facilities.

The Onion Skin Ampoule Filler Sealer ensures consistent and reliable filling and sealing for each ampoule Lodha Pharma — and with pre-gassing and post-gassing stages built into the automated sequence, the machine fully supports inert nitrogen gas flushing to protect oxidation-sensitive pharma APIs, Ayurvedic phytochemical preparations, and cosmetic actives like vitamin C serums, retinol solutions, and plant-based extracts from atmospheric degradation during the filling process.

The Onion Skin Ampoule Filler Sealer is versatile and suitable for a variety of liquid products, including those used in cosmetics and pharmaceuticals Lodha Pharma — making it the ideal specialized filling solution for cosmetic brands producing premium beauty ampoules with the distinctive onion skin finish, including vitamin C serums, hyaluronic acid treatments, hair growth actives, anti-aging peptide formulations, and other high-value cosmetic liquid preparations.

Absolutely. The machine's sterile filling environment, pre-gassing and post-gassing capability, fully hands-free ampoule collection, and SS 316L contact parts make it fully suitable for Ayurvedic manufacturers producing sterile herbal eye drops, plant-based injectables, and other Ayurvedic sterile liquid formulations that require the specific onion skin ampoule format for a clean, safe, and splinter-free breakpoint for end users.

The pendant type electrical control panel is lifted from the machine for ease of operation and safety Lodhapharma — this elevated pendant design keeps all electrical components completely clear of the liquid filling and cleaning zones, significantly reducing electrical hazard risk for operators while providing comfortable, ergonomic access to all machine controls during high-speed pharma, Ayurvedic, and cosmetic ampoule production runs.

The Onion Skin Ampoule Filling Machine is specially designed to give a solution for pharmaceutical, biotech, chemical, and cosmetic industries to fill a range of liquids with viscosities from free flowing to heavy oils Lodhapharma — making it equally capable of handling thin aqueous pharma injectables, Ayurvedic herbal liquid extracts, light cosmetic serums, and thicker cosmetic oils or viscous specialty formulations in the onion skin ampoule format.

The machine has minimum change over parts from 1ml to 20ml ampoule size Lodha Pharma — this minimal changeover part design means pharma, Ayurvedic, and cosmetic manufacturers can quickly switch between different ampoule size formats with the fewest possible part swaps, keeping production line downtime to an absolute minimum and maximizing overall equipment efficiency across multi-SKU product portfolios.

The synchronized star wheel delivers ampoules one by one on the moving eccentric ampoule rack in single, two, four, or six Lodha Pharma — meaning Lodha Pharma's Onion Skin Ampoule Filling Machine is available in single, double, four-head, and six-head configurations to match the exact production volume requirements of small Ayurvedic batch manufacturers right through to high-volume pharma injectable and cosmetic ampoule production lines.

Lodha designs the Ampoule Filling and Sealing Machine as per their standard model as well as custom made models according to customer's specific requirements Lodha Pharma — whether you need a specific head count, custom fill volume range, modified ampoule neck centering system, specialized sealing configuration, clean room enclosure, or sterilization tunnel connection — Lodha Pharma's engineering team can tailor the Onion Skin Machine precisely to your pharma, Ayurvedic, or cosmetic manufacturing needs.

What Pharmaceutical Manufacturers Say About Us

Verified reviews from pharmaceutical manufacturers running our equipment.

Very good quality pharmaceutical machinery manufacturer. Using tablet press machine, ointment tube filling line, Liquid Filling Line and ancillary equipments from last 3 years. Good quality machines and support

U Urvashi Jain

Very High Quality Pharmaceutical Machines. Our company using capsule filling and tablet manufacturing line from this company... Very nice service and support. Recently ordered rotary tube filling machine. Specially thanks to Mr. Dhananjay and Team for support

V Vanshi Sharma

Top-notch pharmaceutical machinery producer located in Ahmedabad. We have been utilizing the Capsule Filling Machine and servo liquid filling machine for the past two years, benefiting from excellent service support provided by LODHA.

A Amit Gupta

High quality pharmaceutical machinery manufacturer in Ahmedabad. We are using liquid filling machine from last 2 years in Australia with great service support by LODHA Team

T Taksh Vyas

Very Good Pharmaceutical Equipment. The best manufacturer of tablet press machines, with excellent assistance from the Lodha team.

A Alka Prajapati

Highly recommended this company for Capsule Machinery and equipment, we purchase Capsule Filling Machine since 3 year and we are very satisfied from that one, & Specifically thanks to Mr. Dhananjay Lodha for always quick support and service.

S Sunayna Rajput

Specially thanks to Mr. Dhananjay Lodha for quick support and service provided for capsule filling machine and tablet press we bought last year. Highly recommended this company for capsule and tablet production equipments.

A Ashok Vaghela

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