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Horizontal Cylindrical Autoclaves

Horizontal Cylindrical Autoclaves

Horizontal Cylindrical Autoclaves Manufacturer

Horizontal Cylindrical Autoclaves, manufactured by LODHA are best suitable for Healthcare and Pharmaceutical industry, where large volume of sterilization is required. Designed ergonomically, our range of high pressure horizontal autoclave sterilizers is ideal for academic facilities, biotech industries, pharmaceutical industries, hospitals, research centres and food and beverage industries. These units efficiently meet stringent sterilization requirements and well suited for sterilizing hospital dressings and surgical instruments, rubber and plastic goods, glassware and utensils etc.

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Salient Features:

  • Vacuum System: Mechanical removal of air initially from within the chamber with the use of a vacuum system ensures    that no air-pockets hinder the steam penetration and hence the sterilization process.
  • Steam Sterilizer for sterilization of varied Hospital equipment like gloves, linen, gauze, cotton, instruments, glassware etc. using    standard 121°C & 134°C cycles which are pre-programmed in the memory of the PLC / Microprocessor
  • Electrical Steam-generator provided for all models up to a chamber volume of 1000 litres.
  • Temperature uniformly and accurately maintained throughout the chamber to within ± 0.5°C of the Set Sterilization temperature.
  • Air Filter: 0.01-micron clean air-filter for stabilization of the internal air-pressure from vacuum condition.
  • Door safety: Door is automatically locked when chamber is under pressure. For double door models, both doors will not open simultaneously to ensure sterile chain integrity.
  • Safety: Jacket and Chamber Safety valves provided.
  • Chamber Fabrication: Chamber fabricated out of SS 304 / S316 grade steel. Heavy duty Steel Jacket encircles and strengthens the chamber.
  • All machines are available with conventional hinged doors, or Modern Automatic sliding door options
  • Double-wall design ensures uniform and rapid pre-heating of the chamber
  • Flush-Mounted panel provided on the sterile side on request, ensuring separation from the un-monitored environment of the operating side.

Steam Sterilizer Sterility assurance through Automation:

  • During Sterilization a Microprocessor / PLC controls temperature, Pressure, Steam Injection, Sterilization time, Drying and all other critical time-based parameters.
  • Important sterilization parameters like Phase Status, Current Values & set values, continuously displayed at all times on Controller Screen & on Remote Computer via SCADA software.
  • Continuous display of Temperature and Pressure On-line allows user to be aware of Cycle status at all times.
  • Error Code and alarm is generated and cycle stops automatically in case any error occurs. Computer Screen displays Error, possible cause and remedy.
  • The advanced SCADA software provided stores detailed records of Process- Data for every cycle.
  • Reports are available in Data, Summary and Graph formats for every batch of goods sterilized.

Models Available:

Model Chamber Diameter (mm) Chamber Depth (mm) Chamber Volume (Litres) Steam Generator Capacity (Litres/KW) Floor Space Required (WxD)
LI-HA1 400 600 79 45/18 1130 x 1900 mm
LI-HA2 400 1100 145 44/9 1130 x 2275 mm
LI-HA3 500 900 185 55/36 1200 x 2300 mm
LI-HA4 500 1200 248 55/36 1200 x 2700 mm
LI-HA5 600 900 268 44/9 1230 x 2400 mm
*Customize specification available on request.

Industries Using Horizontal Cylindrical Autoclaves

  • Pharmaceutical Industry Sterilising containers, closures and equipment before aseptic filling.
  • Vaccine Industry Terminal and dry-heat sterilisation for vaccine production.
  • Biopharmaceutical Industry Depyrogenation and sterilisation for biological processes.
  • Ayurvedic Industry Sterilising glassware for herbal injectables and liquid products.
  • Laboratories & Research Centers Laboratory glassware and media sterilisation.
  • Cosmetic Industry Container sterilisation for preservative-free formulations.

Horizontal Cylindrical Autoclaves FAQs

It uses high-pressure saturated steam inside a cylindrical chamber to eliminate bacteria, spores, fungi, and viruses, making it a reliable sterilization solution for pharma, Ayurvedic, and cosmetic facilities.

The horizontal design enables easy trolley and tray loading, improving batch efficiency, speed, and ergonomic handling in high-volume environments.

Yes — it sterilizes herbal raw materials, vessels, filling equipment, and packaging components to meet GMP and AYUSH standards.

It sterilizes mixing tools, containers, nozzles, and contact parts to prevent microbial contamination and extend product shelf life.

Common cycles operate at 121°C (15–20 minutes) or 134°C (3–5 minutes) at 15–30 PSI for complete sterilization.

The inner chamber is SS 316L stainless steel, while the outer shell is SS 304 — both pharma-grade and pressure-vessel compliant.

Yes — slow exhaust cycles ensure safe sterilization of liquid loads without breakage or spillage.

Yes — reputable models meet WHO-GMP, revised Schedule M, CE, and ASME pressure vessel standards.

It includes a safety relief valve, door interlock system, temperature and pressure alarms, and emergency stop controls.

Capacities range from 50 liters to 3000+ liters, with customization available.

Yes — PLC touchscreen controls with data logging ensure GMP documentation and audit trails.

A complete cycle typically takes 45–90 minutes depending on load and temperature settings.

Yes — breathable packaging and vacuum cycles allow proper steam penetration for herbal materials.

Yes — double-door models support sterile barriers between non-classified and cleanroom areas.

After the sterilization hold phase, a vacuum pump reduces chamber pressure to evaporate residual moisture from porous and wrapped loads. This ensures garments, instruments, and equipment parts exit completely dry and ready for immediate use in cleanroom or production environments.

Common cosmetic loads include empty cream jars, applicators, mixing tools, silicone gaskets, filling nozzles, protective garments, and stainless-steel contact parts — all critical components that must remain contamination-free before production.

Yes — it includes thermocouple validation ports, calibration certificates, and supports full Installation Qualification (IQ), Operational Qualification (OQ), and Performance Qualification (PQ) protocols as required by pharma regulatory authorities.

A self-generating autoclave includes an inbuilt electric steam generator, making it ideal for smaller Ayurvedic and cosmetic units. A plant steam-connected model uses centralized boiler steam and is better suited for large-scale pharma facilities with existing steam infrastructure.

Preventive maintenance is recommended every 3–6 months, while temperature and pressure calibration should be performed at least annually — or as defined in your facility's SOP and validation schedule.

By minimizing contamination-related batch failures, improving audit readiness, and enabling faster production turnaround, most pharma and Ayurvedic companies recover their investment within 12–18 months of consistent operation.

What Pharmaceutical Manufacturers Say About Us

Verified reviews from pharmaceutical manufacturers running our equipment.

Very good quality pharmaceutical machinery manufacturer. Using tablet press machine, ointment tube filling line, Liquid Filling Line and ancillary equipments from last 3 years. Good quality machines and support

U Urvashi Jain

Very High Quality Pharmaceutical Machines. Our company using capsule filling and tablet manufacturing line from this company... Very nice service and support. Recently ordered rotary tube filling machine. Specially thanks to Mr. Dhananjay and Team for support

V Vanshi Sharma

Top-notch pharmaceutical machinery producer located in Ahmedabad. We have been utilizing the Capsule Filling Machine and servo liquid filling machine for the past two years, benefiting from excellent service support provided by LODHA.

A Amit Gupta

High quality pharmaceutical machinery manufacturer in Ahmedabad. We are using liquid filling machine from last 2 years in Australia with great service support by LODHA Team

T Taksh Vyas

Very Good Pharmaceutical Equipment. The best manufacturer of tablet press machines, with excellent assistance from the Lodha team.

A Alka Prajapati

Highly recommended this company for Capsule Machinery and equipment, we purchase Capsule Filling Machine since 3 year and we are very satisfied from that one, & Specifically thanks to Mr. Dhananjay Lodha for always quick support and service.

S Sunayna Rajput

Specially thanks to Mr. Dhananjay Lodha for quick support and service provided for capsule filling machine and tablet press we bought last year. Highly recommended this company for capsule and tablet production equipments.

A Ashok Vaghela

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