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Single Head Ampoule Filling and Sealing Machine

Single Head Ampoule Filling & Sealing Machine

Single Head Ampoule Filling and Sealing Machine Manufacturer

Single Head Ampoule Filling and Sealing Machine designed to give a solution for pharmaceutical, Biotech, Chemical and Cosmetic industry to fill a range of liquids with viscosities from free flowing to heavy Oils. Built on principle of slant travel of ampoules while filling and sealing, to take care of vide variation of ampoule neck dimensions, thicknesses of available standard ampoules. Our glass ampoule filling and sealing machine model LI-AFS 1 can fill different type of containers like: ampoules, vials, glass tubes, onion skin tubes and many others.
The Filling unit built on S. S. Square pipe frame and totally encompassed with S. S. Coverings, in pleasing matt finish, Further, the large opening available at the bottom side for ease of absolute cleaning.
The pendant type electrical control panel is lifted from machine for ease of operation and safety.

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Single Head Ampoule Filling and Sealing Machine Salient Features

  • Compact GMP model
  • All contact parts made from high quality Stainless Steel 316 & other Non-contact parts made from Stainless Steel 304
  • Minimum change over parts from 1ml to 20ml ampoule size
  • “No Ampoule – No Filling” system
  • Ampoule neck centering during gas flushing and filling operations
  • Possibility of nitrogen gas flushing before, during and after filling
  • Full accessibility allows easy maintenance
  • Machine equipped with pre-warming station
  • Minimum change over time, little maintenance & easy cleaning

Single Head Ampoule Filling and Sealing Machine Process Operation

The sterilized ampoule tray directly loaded in to slant hopper of the unit. The Synchronized star wheel delivers ampoules, one by one on moving eccentric ampoule rack in single.
During the stoppage of rack sequentially pre-gassing, filling, post gassing, pre-heating and final sealing is achieved.

Technical Specification of Single Head Ampoule Filling and Sealing Machine

Model No. LI-AFS 1
No. of Head Single
Ampoule Filling Range 1 ml to 20 ml
Production Output 15 to 30 ampoules/minute
Filling Accuracy ± 1%
Require Gas for Sealing LPG & Oxygen (O₂)
Nitrogen Flushing Pre-& Post Nitrogen Flushing Available
Power Specification 0.5 H. P
Electrical Characteristics 230 Volts, Single Phase, 50 Hertz, 4 Wire System
Contact Parts Made from Stainless Steel 316L
Non-Contact Parts Made from Stainless Steel 304
Overall Dimension 915mm (L) x 610mm (W) x 965mm (H)
* Specification can be changed as per customers’ requirements

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Industries Using Single Head Ampoule Filling and Sealing Machine

  • Pharmaceutical Industry Sterile injectable filling and hermetic sealing of glass ampoules.
  • Vaccine Industry Single-dose vaccine and biological filling.
  • Biopharmaceutical Industry Biologicals and high-value formulations in small volumes.
  • Ayurvedic Industry Herbal injectables and ark preparations in sealed ampoules.
  • Cosmetic Industry Ampoule-based serums and single-dose skincare.
  • Laboratories & Research Centers Pilot batches and stability-study filling.

Single Head Ampoule Filling and Sealing Machine FAQs

The Single Head Ampoule Filling and Sealing Machine Model LI-AFS 1 is specially designed to give a solution for pharmaceutical, biotech, chemical, and cosmetic industry to fill a range of liquids with viscosities from free flowing to heavy oils Pharmafillermachines — making it the ideal entry-level automated ampoule solution for small pharma units, Ayurvedic sterile preparation startups, and boutique cosmetic ampoule brands that need professional-grade accuracy without the investment of a multi-head production machine.

The machine model LI-AFS 1 can fill different types of containers like ampoules, vials, glass tubes, onion skin tubes, and many others Pharmafillermachines — giving pharma, Ayurvedic, and cosmetic manufacturers exceptional container format versatility from a single compact machine, covering injectables, sterile eye drops, herbal liquid vials, and premium cosmetic glass tube formats all on one production platform.

Single Head Ampoule Filling and Sealing Machine is a compact GMP model Lodha Pharma — with a production output of up to 30 ampoules per minute depending on liquid nature, ampoule neck diameter, and fill volume — making it perfectly sized for small-batch pharma injectable production, Ayurvedic sterile formulation pilot batches, and cosmetic ampoule trial runs that need consistent quality without high-volume throughput.

The single head configuration delivers the perfect balance of automation and control for manufacturers running frequent batch changeovers across multiple product formulations — Ayurvedic companies producing several sterile herbal preparations and cosmetic brands filling diverse active ampoule SKUs benefit greatly from the quick changeover, easy cleaning, and consistent fill accuracy of the single head design.

Built on the principle of slant travel of ampoules while filling and sealing to take care of wide variation of ampoule neck dimensions and thicknesses of available standard ampoules Pharmafillermachines — this engineering design ensures jam-free, reliable processing of real-world ampoule batches that inevitably have slight dimensional variations in neck size or wall thickness, preventing costly production stoppages and glass breakages during automated filling and sealing cycles.

The sterilized ampoule tray is directly loaded into the slant hopper of the unit — the synchronized star wheel delivers ampoules one by one on the moving eccentric ampoule rack in single — during the stoppage of the rack, sequentially pre-gassing, filling, post gassing, pre-heating, and final sealing is achieved Pharmafillermachines — delivering a fully automated, contamination-free production cycle in a compact single-head format ideal for small pharma, Ayurvedic, and cosmetic batch production.

Duly filled and sealed ampoules are then collected on the collection tray automatically without hand touch Lodha Pharma — this hands-free automatic collection system eliminates any risk of post-fill human contamination, ensuring that every sealed ampoule maintains complete sterile integrity from filling through to packaging — a critical requirement for pharma injectable, Ayurvedic sterile, and cosmetic ampoule products.

All contact parts are made from high quality Stainless Steel 316L and other non-contact parts are made from Stainless Steel 304 Lodha Pharma — meeting cGMP, WHO-GMP, and US FDA material compliance standards required for sterile pharmaceutical injectables, Ayurvedic sterile preparations, and premium cosmetic ampoule products — ensuring zero contamination risk, full corrosion resistance, and easy sterilization between batches.

The filling unit is built on SS square pipe frame and totally encompassed with SS coverings in pleasing matt finish — further, the large opening available at the bottom side for ease of absolute cleaning Lodha Pharma — delivering a robust, hygienic, cGMP-compliant structure that is visually clean, audit-ready, and easy to thoroughly sanitize inside regulated pharma, Ayurvedic, and cosmetic clean room manufacturing environments.

The pendant type electrical control panel is lifted from the machine for ease of operation and safety Lodha Pharma — this elevated pendant design keeps all electrical components completely clear of the liquid filling and cleaning zones, significantly reducing electrical hazard risk while providing ergonomic, easy access to all machine controls for pharma, Ayurvedic, and cosmetic production operators during daily filling and sealing runs.

The machine offers the possibility of nitrogen gas flushing before, during, and after filling Lodhapharma — a critical feature for pharma manufacturers producing oxidation-sensitive injectable APIs, Ayurvedic plant-based sterile preparations containing volatile phytochemicals, and cosmetic ampoules filled with vitamin C serums, retinol solutions, and other high-value actives that rapidly degrade without inert atmosphere protection during the filling process.

The machine is equipped with a "No Ampoule – No Filling" system Lodha Pharma — automatically pausing the fill cycle whenever an ampoule is absent from the transport rack — preventing expensive liquid wastage, nozzle contamination, and product spillage that are especially costly when filling high-value pharma injectables, Ayurvedic sterile formulations, or premium cosmetic ampoule products in single-head small batch production.

The machine is equipped with a pre-warming station Lodhapharma — this gently pre-heats each ampoule neck before the final sealing flame is applied, ensuring a consistent, clean, and hermetically secure onion skin or pull-seal tip closure — preventing micro-leaks, poorly formed seals, and cosmetically defective tip closures that increase batch rejection rates across pharma injectable, Ayurvedic sterile liquid, and cosmetic ampoule production runs.

Centering of ampoule necks during pre-heating, post heating, gas flushing, and liquid filling — rotation of ampoules neck in the pre-heating and heating station Lodhapharma — ensures that every ampoule is perfectly positioned and rotated at each critical stage of the filling and sealing cycle, delivering consistent fill accuracy and a uniform, high-quality hermetic seal on every single ampoule produced.

Single Head Ampoule Filling and Sealing Machine by Lodha is specially designed to give a solution for pharmaceutical, biotech, chemical, and cosmetic industry to fill a range of liquids with viscosities from free flowing to heavy oils Lodha Pharma — making it perfectly suited for cosmetic brands producing vitamin C ampoules, hyaluronic acid serums, collagen boosters, essential oil glass ampoules, and other high-value cosmetic liquid preparations that demand professional-grade fill accuracy and hermetic sealing quality.

Minimum change over parts from 1ml to 10ml ampoule size Lodha Pharma — this minimal changeover part design means pharma, Ayurvedic, and cosmetic manufacturers can quickly switch between different ampoule size formats with the fewest possible part swaps, keeping production line downtime to an absolute minimum and maximizing overall equipment efficiency across multi-SKU product portfolios on a single compact machine.

Absolutely. Full accessibility allows easy maintenance with minimum changeover time, little maintenance, and easy cleaning Lodha Pharma — combined with its single-head compact footprint, the LI-AFS 1 is one of the most practical choices for pharma R&D labs, Ayurvedic product development units, and cosmetic innovation teams that need a reliable, cGMP-compliant ampoule filling and sealing machine for small-scale validation, trial batches, and process development work.

This prevents the ampoules from getting adulterated and hence the medicinal value is preserved — the ampoule filling sealing machine is a highly automated machine that helps in imparting high efficiency and reduces the manpower required for the operation, hence the error caused due to labor is reduced to an optimum level Lodha Pharma — ensuring every ampoule filled by your pharma, Ayurvedic, or cosmetic unit maintains full therapeutic and product potency from production through to the end consumer.

Lodha designs the Ampoule Filling and Sealing Machine as per their standard model as well as custom made models according to customer's specific requirements Lodhapharma — whether you need a specific fill volume range, modified centering system, specialized sealing configuration, clean room enclosure, or connection to upstream sterilization equipment — their engineering team can tailor the LI-AFS 1 precisely to your pharma, Ayurvedic, or cosmetic manufacturing needs and regulatory compliance requirements.

What Pharmaceutical Manufacturers Say About Us

Verified reviews from pharmaceutical manufacturers running our equipment.

Very good quality pharmaceutical machinery manufacturer. Using tablet press machine, ointment tube filling line, Liquid Filling Line and ancillary equipments from last 3 years. Good quality machines and support

U Urvashi Jain

Very High Quality Pharmaceutical Machines. Our company using capsule filling and tablet manufacturing line from this company... Very nice service and support. Recently ordered rotary tube filling machine. Specially thanks to Mr. Dhananjay and Team for support

V Vanshi Sharma

Top-notch pharmaceutical machinery producer located in Ahmedabad. We have been utilizing the Capsule Filling Machine and servo liquid filling machine for the past two years, benefiting from excellent service support provided by LODHA.

A Amit Gupta

High quality pharmaceutical machinery manufacturer in Ahmedabad. We are using liquid filling machine from last 2 years in Australia with great service support by LODHA Team

T Taksh Vyas

Very Good Pharmaceutical Equipment. The best manufacturer of tablet press machines, with excellent assistance from the Lodha team.

A Alka Prajapati

Highly recommended this company for Capsule Machinery and equipment, we purchase Capsule Filling Machine since 3 year and we are very satisfied from that one, & Specifically thanks to Mr. Dhananjay Lodha for always quick support and service.

S Sunayna Rajput

Specially thanks to Mr. Dhananjay Lodha for quick support and service provided for capsule filling machine and tablet press we bought last year. Highly recommended this company for capsule and tablet production equipments.

A Ashok Vaghela

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