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Laboratory Autoclaves & Sterilizers

Autoclaves

Autoclaves Manufacturer

Steam Sterilizers/ Autoclaves are an essential part of the decontamination and sterilization process performed by sterile processing departments in pharmaceutical and healthcare industries. LODHA offers the broadest range of steam sterilizers available on the market. LODHA autoclaves are manufactured in a state of the art facility in compliance with cGMP guidelines to meet the technical challenges of Life-Science, Biotech and HealthCare Industry. Our autoclaves provide precise control and reliable sterile processing and pasteurization. The production facility in the pharmaceutical industry are aimed at maximum safety, top quality and high efficiency. This applies specially for the sterilization process. Autoclave/ Steam Sterilizer continues to be one of the ancient but widely used sterilization techniques in the Life-Science and HealthCare Industry. The process systems now have to meet the most exacting demands for temperature and pressure / Vacuum control and process documentation. A sterilization system represents Therefore, LODHA takes measures to ensure that our Sterilizers provide and life cycle economy. Every Sterilizer is produced to your specifications and needs. Flexible options allow selection of the right equipment for each specific sterilization load and packaging and designed to conform to end-user requirements (URS) and quality assurance processes.

Pharmaceutical Steam Sterilizer is widely used for the sterilization process. It performs the sterilization process by supplying dry and saturated steam under pressure into the autoclave. This high-tech machine uses steam to perform sterilization. Pharmaceutical Steam Sterilizer is used for the sterilization of surgical instruments, clothes, rubber items, plastic, metal, and glassware. However, the technical specification and features of the Pharmaceutical Steam Sterilizer depends on the manufacturer.

Pharmaceutical Steam Sterilizer

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Applications of Autoclave:

  • Porous materials like cotton gauge, garments, fabrics, etc.
  • Closures, Vessels, Machine, Medical Instruments and change parts.
  • Empty Glassware, Utensils, Instruments.
  • Solutions in glass ampoules, vials & bottles.
  • Filters and respective accessories.
  • Solid materials

Salient Features of Steam Sterilizer:

  • Vent filters with automatic sterilization in place and attachments for water-Intrusion-Test.
  • Option of jacket cooling for liquid loads.
  • Electrically heat steam generator for Laboratories & Research Intuitions.
  • Attachments for steam quality testing as per EN285 norms.
  • Facility for terminal sterilization of glass containers with atomized water spray with air over pressure and jacket cooling.
  • Option for vacuum least testing of sealed ampoules.
  • Sanitary design for piping & valves with dead leg <1.50 and slope >2%.
  • Comprehensive test programs, Vacuum Leak Test, Bowie & Dick Test & Pressure Leak Test to safeguard your process and machine.

Industries Using Laboratory Autoclaves & Sterilizers

  • Pharmaceutical Industry Sterilising containers, closures and equipment before aseptic filling.
  • Vaccine Industry Terminal and dry-heat sterilisation for vaccine production.
  • Biopharmaceutical Industry Depyrogenation and sterilisation for biological processes.
  • Ayurvedic Industry Sterilising glassware for herbal injectables and liquid products.
  • Laboratories & Research Centers Laboratory glassware and media sterilisation.
  • Cosmetic Industry Container sterilisation for preservative-free formulations.

Autoclaves FAQs

An autoclave is a pressurized steam sterilization device that destroys bacteria, fungi, spores, and viruses, making it indispensable for GMP-compliant pharma, Ayurvedic, and cosmetic production facilities.

It uses saturated steam at 121°C–134°C to denature microbial proteins and destroy cell structures. Steam transfers heat rapidly and penetrates loads efficiently.

Vertical, horizontal cylindrical, horizontal rectangular, pass-through, and portable autoclaves are available depending on load type and facility scale.

A vertical or compact horizontal cylindrical autoclave is ideal for small to mid-scale Ayurvedic manufacturers.

Yes — stainless steel tools, glass containers, rubber seals, and heat-stable packaging can be sterilized effectively.

Gravity cycles displace air naturally, while pre-vacuum cycles actively remove air to improve steam penetration for dense or wrapped loads.

They include validated cycle controls, temperature sensors, and audit-ready data logging required under WHO-GMP and Schedule M.

SAL of 10⁻⁶ means less than one in a million units may remain non-sterile — the global pharma benchmark.

Yes — breathable packaging and pre-vacuum cycles allow effective steam penetration for herbal materials.

Safety valve, door interlock, over-temperature alarms, pressure gauges, and emergency stop controls.

BI spores confirm sterilization effectiveness during validation cycles — mandatory for GMP compliance.

At least annually or after major repairs, relocation, or parameter changes.

A dual-door system that prevents cross-contamination between clean and non-clean zones.

USFDA-regulated facilities require secure electronic data logging with audit trails.

A 200–750 litre chamber is typically sufficient for mid-size cosmetic operations.

Yes — slow exhaust cycles protect liquid media and culture broths from boiling over.

A well-maintained autoclave lasts 15–25 years with proper preventive maintenance.

It eliminates microbial contamination risks before production, preventing costly recalls.

Self-generating models include a built-in boiler, while external models connect to plant steam for large-scale operations.

Selection depends on load type, batch size, regulatory requirements, steam availability, space, and budget — consulting an experienced GMP-compliant manufacturer is recommended.

What Pharmaceutical Manufacturers Say About Us

Verified reviews from pharmaceutical manufacturers running our equipment.

Very good quality pharmaceutical machinery manufacturer. Using tablet press machine, ointment tube filling line, Liquid Filling Line and ancillary equipments from last 3 years. Good quality machines and support

U Urvashi Jain

Very High Quality Pharmaceutical Machines. Our company using capsule filling and tablet manufacturing line from this company... Very nice service and support. Recently ordered rotary tube filling machine. Specially thanks to Mr. Dhananjay and Team for support

V Vanshi Sharma

Top-notch pharmaceutical machinery producer located in Ahmedabad. We have been utilizing the Capsule Filling Machine and servo liquid filling machine for the past two years, benefiting from excellent service support provided by LODHA.

A Amit Gupta

High quality pharmaceutical machinery manufacturer in Ahmedabad. We are using liquid filling machine from last 2 years in Australia with great service support by LODHA Team

T Taksh Vyas

Very Good Pharmaceutical Equipment. The best manufacturer of tablet press machines, with excellent assistance from the Lodha team.

A Alka Prajapati

Highly recommended this company for Capsule Machinery and equipment, we purchase Capsule Filling Machine since 3 year and we are very satisfied from that one, & Specifically thanks to Mr. Dhananjay Lodha for always quick support and service.

S Sunayna Rajput

Specially thanks to Mr. Dhananjay Lodha for quick support and service provided for capsule filling machine and tablet press we bought last year. Highly recommended this company for capsule and tablet production equipments.

A Ashok Vaghela

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