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Industrial Ethylene Oxide Sterilizer

Industrial Ethylene Oxide Sterilizer

Industrial Ethylene Oxide Sterilizer Manufacturer

Ethylene Oxide Sterilizers are designed to perform low temperature, chemical sterilization treatment of medical, food and pharmaceutical products sensitive to temperature/ humidity. LODHA ETO gas Sterilizers kill the toughest of microbes but are gentle enough to protect the integrity of the product and packaging. A wide range of program options, installation arrangements and loading options increases the versatility. Whether you use external preconditioning and aeration or our unique Combined Process Systems, LODHA can offer customized solutions for your most exacting needs.
ETO Gas Sterilizers operate with a sterilant which is potentially explosive. Hence these Sterilizers incorporate design features, devices & additional means of protection in order to operate in potentially explosive atmosphere in conformity with the established parameters ensuring a very high level of protection against explosions.

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Applications:

  • Health Care Industry: Syringes, Catheters, Cartridges & Dialysis, Sutures, IV Sets, Plastic Articles, Heat Sensitive Rubber Products, Surgical Gloves.
  • Pharmaceutical Industry: Thermo stable basic pharmaceutical products and chemical compounds.
  • Food Industry: Spices and Herbs

Salient Features:

  • Double gasket for improved & fails proof door sealing.
  • Screw Vacuum Pumps & Roots Blowers for applications which require ultra-high vacuum.
  • Flame Proof design for your maximum safety.
  • Gas station with manifold fitted with air regulators, pressure switches, safety release valves and load cell for controlled injection of sterilant.
  • Energy efficient, jacket and door heating system for uniform temperature distribution.
  • Gas Circulation Blower for uniform concentration of sterilant & temperature distribution
  • HI/LO temperature & pressure alarms.
  • Gas detection system with audio-visual alarm to prevent gas leakages. Flame proof.
  • Evacuation hoods to evacuate any residual traces of Ethylene Oxide.
  • Emergency evacuation system for rapid evacuation of the gas in case of emergency.

Industries Using Industrial Ethylene Oxide Sterilizer

  • Pharmaceutical Industry Sterilising containers, closures and equipment before aseptic filling.
  • Vaccine Industry Terminal and dry-heat sterilisation for vaccine production.
  • Biopharmaceutical Industry Depyrogenation and sterilisation for biological processes.
  • Ayurvedic Industry Sterilising glassware for herbal injectables and liquid products.
  • Laboratories & Research Centers Laboratory glassware and media sterilisation.
  • Cosmetic Industry Container sterilisation for preservative-free formulations.

Industrial Ethylene Oxide Sterilizer FAQs

It is a large-capacity, high-throughput low-temperature sterilization system designed for bulk industrial production, unlike smaller hospital ETO units used for limited loads.

ETO operates at 37°C–63°C, preserving APIs, herbal extracts, and polymer packaging that would degrade under steam or dry heat sterilization.

Prefilled syringes, sutures, wound dressings, implants, transdermal patches, medical devices, and heat-sensitive powders.

Yes — for bulk herbal powders and packaged health products requiring validated bioburden reduction without affecting potency.

It sterilizes heat-sensitive packaging, applicators, and finished cosmetic products to ensure safety and export compliance.

ETO concentration 450–1200 mg/L, temperature 37°C–63°C, RH 40%–80%, exposure 2–6 hours to achieve SAL 10⁻⁶.

ISO 11135, ISO 10993-7, USP 1229.1, WHO-GMP, Schedule M, and applicable USFDA/EU-GMP requirements.

Gas-tight chambers, leak detectors, safety interlocks, negative pressure design, and catalytic abatement systems ensure operator and environmental safety.

Post-sterilization aeration removes residual ETO and byproducts to safe ISO 10993-7 limits before product release.

Typically 24–72 hours including conditioning, exposure, evacuation, and aeration.

From 1 m³ to 30+ m³, processing 500 kg to several tonnes per cycle.

Using validated gas chromatography (GC) methods to ensure compliance with ISO residual limits.

IQ, OQ, PQ, biological indicator testing, half-cycle studies, and residual ETO verification.

Validated ISO-compliant sterilization supports USFDA, EU-GMP, and international market submissions.

100% ETO offers superior penetration; ETO-CO2 blends reduce flammability risk.

Yes — PLC systems support 21 CFR Part 11 compliance and full electronic batch documentation.

Compliance with CPCB guidelines, Hazardous Chemical Rules 1989, and Fire Safety regulations.

It converts exhaust ETO gas into non-toxic byproducts using catalytic oxidizers or scrubbers.

Installation, IQ/OQ/PQ support, training, spare parts, calibration, and annual maintenance services.

Selection depends on sterilization volume, product type, utilities, regulatory targets, and long-term production planning.

What Pharmaceutical Manufacturers Say About Us

Verified reviews from pharmaceutical manufacturers running our equipment.

Very good quality pharmaceutical machinery manufacturer. Using tablet press machine, ointment tube filling line, Liquid Filling Line and ancillary equipments from last 3 years. Good quality machines and support

U Urvashi Jain

Very High Quality Pharmaceutical Machines. Our company using capsule filling and tablet manufacturing line from this company... Very nice service and support. Recently ordered rotary tube filling machine. Specially thanks to Mr. Dhananjay and Team for support

V Vanshi Sharma

Top-notch pharmaceutical machinery producer located in Ahmedabad. We have been utilizing the Capsule Filling Machine and servo liquid filling machine for the past two years, benefiting from excellent service support provided by LODHA.

A Amit Gupta

High quality pharmaceutical machinery manufacturer in Ahmedabad. We are using liquid filling machine from last 2 years in Australia with great service support by LODHA Team

T Taksh Vyas

Very Good Pharmaceutical Equipment. The best manufacturer of tablet press machines, with excellent assistance from the Lodha team.

A Alka Prajapati

Highly recommended this company for Capsule Machinery and equipment, we purchase Capsule Filling Machine since 3 year and we are very satisfied from that one, & Specifically thanks to Mr. Dhananjay Lodha for always quick support and service.

S Sunayna Rajput

Specially thanks to Mr. Dhananjay Lodha for quick support and service provided for capsule filling machine and tablet press we bought last year. Highly recommended this company for capsule and tablet production equipments.

A Ashok Vaghela

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