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High Speed Ampoule Filling & Sealing Machine

High Speed Ampoule Filling and Sealing Machine

High Speed Ampoule Filling & Sealing Machine Manufacturer

High Speed Ampoule Filling & Sealing Machine Model LI-AFS 8 built on principle of slant travel of ampoules while filling and sealing, to take care of vide variation of ampoule neck dimensions, thicknesses of available standard ampoules.
The Filling unit built on S. S. Square pipe frame and totally encompassed with S. S. Coverings, in pleasing matt finish, Further, the large opening available at the bottom side for ease of absolute cleaning.
The pendant type electrical control panel is lifted from machine for ease of operation and safety.

The ampoule filling & sealing machine is a compact machine and performs the dual operation of filling and sealing. It is highly used in pharmaceutical industries as its highly precise operation helps in achieving advanced and high output rates. The ampoule filler sealer machine seals the ampules by placing stoppers over their head. This prevents the ampoules from getting adulterated and hence the medicinal value is preserved. The machine requires very little change over time and hence is quite easy to maintain & clean. Ampoule filling & sealing machine is built using SS that imparts durability thus making it suitable for prolonged operations. The filling station of ampoule filler and sealer machine may consist of multiple heads ranging from two to eight. Multiple heads are used for increased production rate as per the requirement. The ampoule filling sealing machine is a highly automated machine that helps in imparting high efficiency. It reduces the manpower required for the operation and hence the error caused due to labor is reduced to an optimum level.

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Salient Features of Ampoule Filling & Sealing Machine

  • Compact GMP model
  • All contact parts of ampoules fill seal equipment made from AISI SS 316L & other Non-contact parts made from AISI SS 304.
  • Minimum change over parts from 1ml to 10ml ampoule size
  • “No Ampoule – No Filling” system
  • Ampoule neck centering during gas flushing and filling operations
  • Possibility of nitrogen gas flushing before, during and after filling
  • Full accessibility allows easy maintenance
  • Ampoule filling sealing machine equipped with pre-warming station
  • Minimum change over time, little maintenance & easy cleaning

Ampoule Filler Sealer Process Operation

The sterilized ampoule tray directly loaded in to slant hopper of the unit. The Synchronized star wheel delivers ampoules one by one on moving eccentric ampoule rack in four’s.
During the stoppage of rack sequentially pre-gassing, filling, post gassing, pre-heating and final sealing is achieved. Duly filled sealed ampoules then collected on collection tray automatically without hand touch.

Technical Specification

Model No. LI-AFS 8
Ampoule Filling Range 1 ml to 10 ml
Production Output 200 ampoules/ min.
Filling Accuracy ±1
Require Gas for Sealing LPG & Oxygen (O₂)
Nitrogen Flushing Pre-& Post Nitrogen Flushing Available
Power Specification 1 H.P.
Electrical Characteristics 230 Volts, Single Phase, 50 Hertz, 4 Wire System
Contact Parts Stainless Steel 316L
Non-Contact Parts Stainless Steel 304
Overall Dimension 1180mm (L) x 1075mm (W) x 975mm (H)
* Specification can be changed as per customers’ requirements

Watch Our High Speed Ampoule Filling & Sealing Machine Video

Industries Using High Speed Ampoule Filling & Sealing Machine

  • Pharmaceutical Industry Sterile injectable filling and hermetic sealing of glass ampoules.
  • Vaccine Industry Single-dose vaccine and biological filling.
  • Biopharmaceutical Industry Biologicals and high-value formulations in small volumes.
  • Ayurvedic Industry Herbal injectables and ark preparations in sealed ampoules.
  • Cosmetic Industry Ampoule-based serums and single-dose skincare.
  • Laboratories & Research Centers Pilot batches and stability-study filling.

High Speed Ampoule Filling & Sealing Machine FAQs

The High Speed Ampoule Filling & Sealing Machine Model LI-AFS 8 is a compact machine that performs the dual operation of filling and sealing and is highly used in pharmaceutical industries as its highly precise operation helps in achieving advanced and high output rates Lodha Pharma — making it the definitive choice for large-scale pharma injectable manufacturers, high-volume Ayurvedic sterile liquid producers, and cosmetic ampoule brands that cannot afford any compromise on speed, accuracy, or sterility.

Using the high speed ampoule filling & sealing machine reduces labor costs and improves production rates Lodhapharma — and with eight filling heads operating simultaneously in a single automated cycle, the LI-AFS 8 delivers significantly higher throughput than lower-head-count models, making it the preferred upgrade path for pharma, Ayurvedic, and cosmetic manufacturers scaling from mid to high-volume production.

The machine can process 10 to 250 ampoules per minute using a volumetric piston-pump filling technique Lodha Pharma — with the eight-head high speed configuration delivering maximum throughput at the top end of this range — making it one of the fastest ampoule filling and sealing solutions available from an Indian pharma machinery manufacturer for large-scale sterile injectable and cosmetic ampoule production.

The machine is built on the principle of slant travel of ampoules while filling and sealing to take care of wide variation of ampoule neck dimensions and thicknesses of available standard ampoules Lodha Pharma — and with the machine capable of filling and sealing ampoules from 1 ml to 25 ml with a single-dose filling capacity ranging from 0.5 ml to 25 ml Lodha Pharma — it covers every ampoule format used in pharma injectables, Ayurvedic sterile preparations, and cosmetic ampoule packaging.

The filling station of ampoule filler and sealer machine may consist of multiple heads ranging from two to eight — multiple heads are used for increased production rate as per the requirement Lodha Pharma — meaning the eight-head configuration of the LI-AFS 8 fills and seals eight ampoules simultaneously in every machine cycle, delivering the highest possible output rate for large-scale pharma injectable, Ayurvedic sterile liquid, and cosmetic ampoule production lines.

All contact parts of ampoule fill seal equipment are made from AISI SS 316L and other non-contact parts are made from AISI SS 304 Lodha Pharma — the highest pharmaceutical-grade stainless steel grades — ensuring zero contamination risk, full corrosion resistance, easy sterilization between batches, and complete compliance with cGMP, WHO-GMP, and US FDA material standards for sterile pharma injectable and Ayurvedic sterile preparation manufacturing.

The sterilized ampoule tray is directly loaded into the slant hopper of the unit — the synchronized star wheel delivers ampoules one by one on the moving eccentric ampoule rack in four's — during the stoppage of the rack, sequentially pre-gassing, filling, post gassing, pre-heating, and final sealing is achieved Lodha Pharma — ensuring a smooth, continuous, and contamination-free ampoule transport and processing flow at high production speeds.

Duly filled and sealed ampoules are then collected on the collection tray automatically without hand touch Lodha Pharma — this fully hands-free automatic collection system eliminates any risk of post-fill human contamination, maintains complete sterile integrity, and ensures every sealed ampoule exiting the high-speed production line is ready for downstream inspection, labelling, and packaging without manual intervention.

The machine features possibility of nitrogen gas flushing before, during and after filling and ampoule neck centering during gas flushing and filling operations Lodha Pharma — making it essential for pharma manufacturers producing oxidation-sensitive APIs, Ayurvedic plant-based sterile preparations, and cosmetic ampoules containing vitamin C, retinol, peptides, and other high-value actives that degrade rapidly without inert atmosphere protection.

The machine is built on the principle of slant travel of ampoules while filling and sealing to take care of wide variation of ampoule neck dimensions, thicknesses, and ovality of available ampoules Lodha Pharma — this engineering design allows the machine to reliably handle real-world ampoule batches that vary slightly in neck diameter or shape, preventing costly jams, breakage, and production stoppages at the high operating speeds of the LI-AFS 8.

The machine is equipped with a "No Ampoule – No Filling" system Lodha Pharma — automatically pausing the fill cycle whenever an ampoule is absent from the transport rack — preventing expensive product spillage, nozzle contamination, and liquid wastage that are especially costly on a high-speed production line processing premium pharma injectables, Ayurvedic sterile formulations, or high-value cosmetic ampoule products.

The machine is equipped with a pre-warming station Lodha Pharma — this gently pre-heats each ampoule neck before the final sealing flame is applied, ensuring a consistent, clean, and hermetically secure seal across all eight heads simultaneously — preventing micro-leaks, poorly formed seals, or cosmetically defective tip closures that increase batch rejection rates on high-speed pharma and cosmetic ampoule production lines.

The machine can use either oxygen or LPG (propane) gas for sealing and filling, making it suitable for different chemicals such as agro-insecticides, veterinary pharmaceuticals, and cosmetic ampoules Lodha Pharma — giving pharma, Ayurvedic, and cosmetic manufacturers the flexibility to use the most appropriate gas combination for their specific product type, ampoule glass thickness, and clean room regulatory requirements.

The filling unit is built on SS square pipe frame and totally encompassed with SS coverings in pleasing matt finish — further, the large opening available at the bottom side for ease of absolute cleaning Lodha Pharma — delivering a robust, hygienic, cGMP-compliant machine structure that is visually clean, audit-ready, and easy to thoroughly sanitize — essential for maintaining clean room integrity in regulated sterile pharma and Ayurvedic manufacturing environments.

The ampoule filling sealing machine is a highly automated machine that helps in imparting high efficiency — it reduces the manpower required for the operation and hence the error caused due to labor is reduced to an optimum level Lodha Pharma — delivering consistent, operator-independent fill accuracy and seal quality across every high-speed production cycle, which is critical for maintaining batch homogeneity in pharma injectables, Ayurvedic sterile liquids, and cosmetic ampoule products.

The high speed ampoule filling unit finds vast applications in pharmaceutical, cosmetic, and chemicals industry Lodha Pharma — making it perfectly suited for cosmetic brands filling premium vitamin C ampoules, hyaluronic acid serums, collagen boosters, anti-aging actives, and other high-value cosmetic liquid preparations in sealed glass ampoules at production volumes that demand the highest-speed filling and sealing solution available.

The machine requires very little changeover time and hence is quite easy to maintain and clean Lodha Pharma — and with the large bottom access opening, fully removable SS 316L contact parts, and pendant control panel lifted safely away from cleaning zones, the LI-AFS 8 is engineered to minimize inter-batch downtime — keeping your high-speed pharma, Ayurvedic, and cosmetic ampoule production schedules consistently on track.

This prevents the ampoules from getting adulterated and hence the medicinal value is preserved Lodha Pharma — through a fully automated, hands-free production sequence combining pre-gassing, precise volumetric filling, post-gassing, pre-warming, and hermetic sealing — the machine ensures every ampoule delivers its full medicinal or active ingredient potency to the end patient or consumer, whether it contains a pharma injectable, Ayurvedic sterile preparation, or cosmetic active.

Specification can be changed as per customers' requirements Lodha Pharma — and Lodha Pharma's engineering team works closely with pharma, Ayurvedic, and cosmetic manufacturers to customize head count, ampoule size range, fill volume, gas type, sealing station configuration, conveyor integration, and clean room enclosure specifications — ensuring the LI-AFS 8 is perfectly tailored to your exact facility layout, product portfolio, and regulatory compliance requirements.

What Pharmaceutical Manufacturers Say About Us

Verified reviews from pharmaceutical manufacturers running our equipment.

Very good quality pharmaceutical machinery manufacturer. Using tablet press machine, ointment tube filling line, Liquid Filling Line and ancillary equipments from last 3 years. Good quality machines and support

U Urvashi Jain

Very High Quality Pharmaceutical Machines. Our company using capsule filling and tablet manufacturing line from this company... Very nice service and support. Recently ordered rotary tube filling machine. Specially thanks to Mr. Dhananjay and Team for support

V Vanshi Sharma

Top-notch pharmaceutical machinery producer located in Ahmedabad. We have been utilizing the Capsule Filling Machine and servo liquid filling machine for the past two years, benefiting from excellent service support provided by LODHA.

A Amit Gupta

High quality pharmaceutical machinery manufacturer in Ahmedabad. We are using liquid filling machine from last 2 years in Australia with great service support by LODHA Team

T Taksh Vyas

Very Good Pharmaceutical Equipment. The best manufacturer of tablet press machines, with excellent assistance from the Lodha team.

A Alka Prajapati

Highly recommended this company for Capsule Machinery and equipment, we purchase Capsule Filling Machine since 3 year and we are very satisfied from that one, & Specifically thanks to Mr. Dhananjay Lodha for always quick support and service.

S Sunayna Rajput

Specially thanks to Mr. Dhananjay Lodha for quick support and service provided for capsule filling machine and tablet press we bought last year. Highly recommended this company for capsule and tablet production equipments.

A Ashok Vaghela

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