Automatic Ampoule Filling & Sealing Machine Servo Based

Automatic Ampoule Filling and Sealing Machine Servo Based
Automatic Ampoule Filling and Sealing Machine Servo Based

Automatic Ampoule Filling and Sealing Machine Servo Based

Ampoule Filling and Sealing Machine with Servo based system have been designed and built in compliance with cGMP standards. The basic design principle and the type of operation offers optimum reliability for conveying the ampoule for the filling (servo based) & sealing process and out-feed. With a wide range of models to suit different formats and production requirements customers will be able to find a machine appropriate to their needs. Machine equipped with PLC & HMI based control panel for auto fill volume adjustments. Machine is having wide range of uses in pharmaceutical, biotech, cosmetic, veterinary & chemical industry. We are continuously developing and modifying Ampoule Filling and Sealing Machine to customer’s specific needs.

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This ampoule filling and sealing machine provides a very smooth and efficient way of filling and sealing ampoules. While choosing the most reliable and high-quality machine manufacturers to ensure maximum productivity, efficiency, and accuracy in operations. It is ensured that the drugs get protected from environmental dust and micro-organisms. A faster changeover of ampoules helps in faster production while also making it easier to handle and store drugs with the right content and amount. The compact and versatile machinery takes care of a wide variation like the neck of containers, its thickness, and its shape or form. They not only allow complete accessibility but also uniqueness and the easiest way of maintenance.

Superiority in operation and performance through modern design construction offer advantages in terms of reliability and operational use.

All the functions of the machine can be seen and easily checked with good accessibility to all the work stations, easy access to the handy change parts and hence easy to install guides because of the tilt-away designed burner station.

The linear conveying system consists of a cam-controlled walking beam, a narrow ampoule slide rail, an upper and lower centering beam with corresponding back up supports as well as the pressure rollers in the sealing area.


Salient Features:

  • Compact GMP model
  • Auto Fill Volume adjustments from Control Panel of the machine.
  • Option of attaching wire mesh conveyor for connection to Sterilization Tunnel.
  • Production output ranging from 25 ampoules/min. to 200 ampoules/min.
  • Co-eccentric nozzles allow very quick and precise filling.
  • All contact parts made from AISI SS 316L & other Non-contact parts made from AISI SS 304.
  • Machine is suitable to fill 1ml to 20ml ampoules in LI-AF 1P & 2P models and 1ml to 10ml in LI-AF 4P, 6P & 8P Models.
  • “No Ampoule – No Filling” system
  • Ampoule neck centering during gas flushing and filling operations
  • Possibility of nitrogen gas flushing before, during and after filling
  • Full accessibility allows easy maintenance
  • Machine equipped with pre-warming station.
  • Minimum change over time, little maintenance & easy cleaning

Process Operation:

  • The sterilized ampoule tray directly loaded in to slant hopper of the unit. The Synchronized star wheel delivers ampoules one by one on moving eccentric ampoule rack in single/two/four/six.
  • During the stoppage of rack sequentially pre-gassing, filling, post gassing, pre heating and final sealing is achieved. Duly filled sealed ampoules then collected on collection tray automatically without hand touch.

The Servo Based machine performs the following operations

  • Ampoule feeding by in-feed hopper, star wheel and ampoules transfer into transport rack.
  • Two ampoules advanced per machine stroke.
  • Centering of ampoules necks during pre-heating, post heating, gas flushing and liquid filling (Servo-based).
  • Rotation of ampoules neck in the pre- heating and heating station.
  • Elimination of burdened-off ampoule tips by clippers and ejection into a separate container.

Technical Specification:

Machine Model LI-AF 1P LI-AF 2P LI-AF 4P LI-AF 6P LI-AF 8P
No. of Head Single Two Four Six Eight
Ampoule Handling Range 1 ml to 20 ml 1 ml to 20 ml 1 ml to 10 ml 1 ml to 10 ml 1 ml to 10 ml
Production Output Up to 25 ampoules/minute Up to 50 ampoules/minute Up to 100 ampoules/minute Up to 150 ampoules/minute Up to 200 ampoules/minute
Filling Accuracy ± 1% ± 1% ± 1% ± 1% ± 1%
Require Gas for Sealing LPG & Oxygen (O2) LPG & Oxygen (O2) LPG & Oxygen (O2) LPG & Oxygen (O2) LPG & Oxygen (O2)
Nitrogen Flushing Pre & Post Nitrogen Flushing Available Pre & Post Nitrogen Flushing Available Pre & Post Nitrogen Flushing Available Pre & Post Nitrogen Flushing Available Pre & Post Nitrogen Flushing Available
Power Specification 0.5 H. P 1 H.P. 1 H.P. 1 H.P. 2 H.P.
Electrical Characteristics 230 Volts, Single Phase, 50 Hertz, 4 Wire System 230 Volts, Single Phase, 50 Hertz, 4 Wire System 230 Volts, Single Phase, 50 Hertz, 4 Wire System 230 Volts, Single Phase, 50 Hertz, 4 Wire System 230 Volts, Single Phase, 50 Hertz, 4 Wire System
Contact Parts Made from Stainless Steel 316L Made from Stainless Steel 316L Made from Stainless Steel 316L Made from Stainless Steel 316L Made from Stainless Steel 316L
Non-Contact Parts Made from Stainless Steel 304 Made from Stainless Steel 304 Made from Stainless Steel 304 Made from Stainless Steel 304 Made from Stainless Steel 304
Overall Dimension 915 mm (L) x 610 mm (W) x 965 mm (H) 915 mm (L) x 760 mm (W) x 965 mm (H) 1200 mm (L) x 1070 mm (W) x 965 mm (H) 1600 mm (L) x 1400 mm (W) x 1400 mm (H) 2350 mm (L) x 1400 mm (W) x 1350 mm (H)
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Faq's

The Servo PLC Based Ampoule Filling Machine integrates servo motor technology and PLC-based control systems, allowing real-time parameter adjustment and providing unmatched flexibility and reliability Lodha Pharma — delivering a level of precision, repeatability, and automation that conventional mechanical ampoule machines simply cannot match for today's demanding pharma, Ayurvedic, and cosmetic production environments.

The Ampoule Filling and Sealing Machine with servo based system has been designed and built in compliance with cGMP standards — the basic design principle and the type of operation offers optimum reliability for conveying the ampoule for the filling (servo based) and sealing process and out-feed Lodha Pharma — making it fully audit-ready for WHO-GMP, US FDA, and EU GMP facility inspections across pharma, Ayurvedic, and cosmetic manufacturing units.

Production output ranges from 25 ampoules per minute to 200 ampoules per minute Lodha Pharma — giving pharma, Ayurvedic, and cosmetic manufacturers the flexibility to choose the right servo-based model configuration that matches their current production volume while leaving room to scale up as business demand grows.

The machine is suitable to fill 1ml to 20ml ampoules in LI-AF 1P and 2P models and 1ml to 10ml in LI-AF 4P, 6P, and 8P Models Lodha Pharma — covering the complete range of ampoule sizes most commonly used by pharma injectable manufacturers, Ayurvedic sterile preparation units, and cosmetic ampoule brands across India and international markets.

The machine is equipped with a PLC and HMI based control panel for auto fill volume adjustments Lodha Pharma — meaning operators can precisely program, monitor, and adjust fill volumes directly from the touchscreen interface — eliminating manual calibration errors, reducing operator skill dependency, and enabling quick recipe-based batch changeovers for multiple product formulations.

Co-eccentric nozzles allow very quick and precise filling Lodha Pharma — this advanced nozzle design ensures that each ampoule receives an exactly measured, drip-free dose of liquid with minimal foaming or splashing — critical for maintaining fill accuracy in pharma injectables, Ayurvedic sterile liquids, and premium cosmetic ampoule formulations.

All contact parts are made from AISI SS 316L and other non-contact parts are made from AISI SS 304 Lodha Pharma — the highest pharmaceutical-grade stainless steel grades — ensuring zero contamination risk, full corrosion resistance, easy sterilization between batches, and complete compliance with cGMP, WHO-GMP, and US FDA material standards.

The centering of ampoules necks during pre-heating, post heating, gas flushing and liquid filling is servo based Lodha Pharma — and with pre-gassing, filling, and post-gassing performed sequentially in the automated cycle, the machine fully supports inert gas flushing to protect oxidation-sensitive pharma APIs, Ayurvedic plant extracts, and cosmetic actives from atmospheric degradation throughout the entire filling process.

The linear conveying system consists of a cam-controlled walking beam, a narrow ampoule slide rail, an upper and lower centering beam with corresponding back up supports as well as the pressure rollers in the sealing area Lodha Pharma — ensuring each ampoule is transported, centered, filled, and sealed with exceptional stability and precision at every stage of the production cycle.

The machine has an option of attaching a wire mesh conveyor for connection to a Sterilization Tunnel Lodha Pharma — allowing pharma manufacturers to build a completely integrated sterile filling line where ampoules move directly from the depyrogenation tunnel to filling and sealing without any manual handling — a critical requirement for injectable-grade sterile pharma facilities and Ayurvedic sterile manufacturing units.

Servo PLC Based Ampoule Filling Machines are perfect for complex or delicate formulations requiring precise filling volumes Lodha Pharma — whether it's a narrow therapeutic index injectable drug, a sensitive Ayurvedic phytochemical preparation, or a premium cosmetic active ampoule, the servo system guarantees the exact fill volume needed to maintain efficacy, safety, and regulatory compliance in every single ampoule.

The machine is equipped with a pre-warming station Lodha Pharma — this gently pre-heats ampoule necks before the final sealing flame is applied, ensuring a consistent, clean, and hermetically secure seal that prevents micro-leaks, maintains product sterility, and significantly reduces the incidence of improperly sealed ampoules in your pharma, Ayurvedic, or cosmetic production batch.

The machine has a wide range of uses in pharmaceutical, biotech, cosmetic, veterinary, and chemical industries Lodha Pharma — with the servo-based model being especially preferred by regulated pharma injectable manufacturers, Ayurvedic sterile preparation companies, and high-end cosmetic ampoule brands where fill accuracy, contamination control, and production traceability are non-negotiable requirements.

The machine requires minimum change over time, little maintenance, and easy cleaning — the sterilized ampoule tray is directly loaded into the slant hopper of the unit Lodha Pharma — and with servo-controlled centering automatically adapting to different ampoule neck dimensions, size changeovers are faster and more reliable than on conventional mechanical ampoule machines, reducing downtime across multiple product lines.

The servo-based filling machine is used in pharmaceutical industry and cosmetic industry and can produce up to 200 ampoules per minute Lodha Pharma — making it perfectly suited for cosmetic brands filling high-value vitamin C ampoules, hyaluronic acid serums, hair growth actives, collagen boosters, and other premium cosmetic liquid preparations in sealed glass ampoules at high speed and with flawless accuracy.

During the stoppage of the rack, sequentially pre-gassing, filling, post gassing, pre-heating, and final sealing is achieved — duly filled and sealed ampoules are then collected on the collection tray automatically without hand touch Pharmafillermachines — maintaining complete sterility throughout the post-fill collection stage, which is critical for regulatory compliance in pharma injectable and Ayurvedic sterile ampoule production.

Servo PLC Based Ampoule Filling Machines allow real-time parameter adjustment, providing unmatched flexibility and reliability Lodha Pharma — unlike conventional cam-driven systems where mechanical wear gradually degrades fill accuracy over time, servo motors maintain consistent, programmable piston stroke control throughout the machine's operational life — delivering batch-after-batch fill consistency for pharma, Ayurvedic, and cosmetic products.

Lodha Pharma offers a wide range of models to suit different formats and production requirements so customers will be able to find a machine appropriate to their needs Lodha Pharma — with available configurations including single head, double head, four head, six head, and eight head models, along with PLC and HMI based automation features as per customer's specific requirements Lodha Pharma — covering every production volume from small Ayurvedic batches to large-scale pharma injectable lines.

Lodha Pharma is continuously developing and modifying the Ampoule Filling and Sealing Machine to customer's specific needs Lodha Pharma — whether you need a specific head count, custom fill volume range, clean room-compatible enclosure, integrated tunnel connection, or specialized sealing configuration — their engineering team works closely with pharma, Ayurvedic, and cosmetic manufacturers to deliver a machine tailored exactly to your facility and product requirements.

What Our Clients Say About Us?

Our clients' feedback is always important for our growth.

We've been using the Manual Capsule Filling Machine from Lodha International LLP for months now. It's efficient and easy to operate. Great value for the investment!

The Automatic Capsule Loader from Lodha International has transformed our production process. It saves us so much time and provides consistent results. Highly recommend it!

Our production line is working much more smoothly, thanks to Lodha International LLP and their Ampoule Filling & Sealing Machine. It's built to last, and the results are always precise.

Our packaging process has never been more efficient since we invested in Lodha International LLP's pharmaceutical packaging machinery. The machinery is reliable and user-friendly. We couldn’t be happier.

We switched to the Automatic Capsule Filling Machine from Lodha International LLP, and the difference is clear. The machine delivers exceptional precision and speed. It greatly enhanced our industrial productivity.

We’ve been using the Manual Capsule Filling Machine for several months and are very impressed with its performance. It's robust, easy to maintain, and ideal for our needs. Highly satisfied with Lodha International LLP.

The Automatic Capsule Loader from Lodha International revolutionizes the industry. It increased our production speed significantly while reducing human error. It is an excellent investment for any pharma company.

We’ve been using Lodha International LLP’s Ampoule Filling & Sealing Machine for a while, and it has exceeded our expectations. The machinery is highly effective in our filling processes.

The Pharmaceutical Packaging Machinery from Lodha International LLP has greatly improved our packaging line. It’s efficient, high-quality, and easy to integrate into our existing system. Highly recommend their products!

We recently upgraded to the Automatic Capsule Filling Machine from Lodha International LLP. The machine is fantastic—fast, precise, and cost-effective. It has made an important difference in our manufacturing quality.

The pharmaceutical machinery from Lodha International LLP. has completely transformed our production line. Excellent performance and long-lasting quality—highly recommended!

Exceptional quality and service! The pharmaceutical machinery delivered consistent output and helped streamline our processes.

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