High Speed Ampoule Filling and Sealing Machine

High Speed Ampoule Filling & Sealing Machine

High Speed Ampoule Filling & Sealing Machine Model LI-AFS 8 built on principle of slant travel of ampoules while filling and sealing, to take care of vide variation of ampoule neck dimensions, thicknesses of available standard ampoules.
The Filling unit built on S. S. Square pipe frame and totally encompassed with S. S. Coverings, in pleasing matt finish, Further, the large opening available at the bottom side for ease of absolute cleaning.
The pendant type electrical control panel is lifted from machine for ease of operation and safety.

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The ampoule filling & sealing machine is a compact machine and performs the dual operation of filling and sealing. It is highly used in pharmaceutical industries as its highly precise operation helps in achieving advanced and high output rates. The ampoule filler sealer machine seals the ampules by placing stoppers over their head. This prevents the ampoules from getting adulterated and hence the medicinal value is preserved. The machine requires very little change over time and hence is quite easy to maintain & clean. Ampoule filling & sealing machine is built using SS that imparts durability thus making it suitable for prolonged operations. The filling station of ampoule filler and sealer machine may consist of multiple heads ranging from two to eight. Multiple heads are used for increased production rate as per the requirement. The ampoule filling sealing machine is a highly automated machine that helps in imparting high efficiency. It reduces the manpower required for the operation and hence the error caused due to labor is reduced to an optimum level.

Salient Features of Ampoule Filling & Sealing Machine

Compact GMP model
All contact parts of ampoules fill seal equipment made from AISI SS 316L & other Non-contact parts made from AISI SS 304.
Minimum change over parts from 1ml to 10ml ampoule size
“No Ampoule – No Filling” system
Ampoule neck centering during gas flushing and filling operations
Possibility of nitrogen gas flushing before, during and after filling
Full accessibility allows easy maintenance
Ampoule filling sealing machine equipped with pre-warming station
Minimum change over time, little maintenance & easy cleaning

Ampoule Filler Sealer Process Operation

The sterilized ampoule tray directly loaded in to slant hopper of the unit. The Synchronized star wheel delivers ampoules one by one on moving eccentric ampoule rack in four’s.
During the stoppage of rack sequentially pre-gassing, filling, post gassing, pre-heating and final sealing is achieved. Duly filled sealed ampoules then collected on collection tray automatically without hand touch.

Technical Specification

Model No.	LI-AFS 8
Ampoule Filling Range	1 ml to 10 ml
Production Output	200 ampoules/ min.
Filling Accuracy	±1
Require Gas for Sealing	LPG & Oxygen (O₂)
Nitrogen Flushing	Pre-& Post Nitrogen Flushing Available
Power Specification	1 H.P.
Electrical Characteristics	230 Volts, Single Phase, 50 Hertz, 4 Wire System
Contact Parts	Stainless Steel 316L
Non-Contact Parts	Stainless Steel 304
Overall Dimension	1180mm (L) x 1075mm (W) x 975mm (H)

* Specification can be changed as per customers’ requirements

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Faq's

The High Speed Ampoule Filling & Sealing Machine Model LI-AFS 8 is a compact machine that performs the dual operation of filling and sealing and is highly used in pharmaceutical industries as its highly precise operation helps in achieving advanced and high output rates Lodha Pharma — making it the definitive choice for large-scale pharma injectable manufacturers, high-volume Ayurvedic sterile liquid producers, and cosmetic ampoule brands that cannot afford any compromise on speed, accuracy, or sterility.

Using the high speed ampoule filling & sealing machine reduces labor costs and improves production rates Lodhapharma — and with eight filling heads operating simultaneously in a single automated cycle, the LI-AFS 8 delivers significantly higher throughput than lower-head-count models, making it the preferred upgrade path for pharma, Ayurvedic, and cosmetic manufacturers scaling from mid to high-volume production.

The machine can process 10 to 250 ampoules per minute using a volumetric piston-pump filling technique Lodha Pharma — with the eight-head high speed configuration delivering maximum throughput at the top end of this range — making it one of the fastest ampoule filling and sealing solutions available from an Indian pharma machinery manufacturer for large-scale sterile injectable and cosmetic ampoule production.

The machine is built on the principle of slant travel of ampoules while filling and sealing to take care of wide variation of ampoule neck dimensions and thicknesses of available standard ampoules Lodha Pharma — and with the machine capable of filling and sealing ampoules from 1 ml to 25 ml with a single-dose filling capacity ranging from 0.5 ml to 25 ml Lodha Pharma — it covers every ampoule format used in pharma injectables, Ayurvedic sterile preparations, and cosmetic ampoule packaging.

The filling station of ampoule filler and sealer machine may consist of multiple heads ranging from two to eight — multiple heads are used for increased production rate as per the requirement Lodha Pharma — meaning the eight-head configuration of the LI-AFS 8 fills and seals eight ampoules simultaneously in every machine cycle, delivering the highest possible output rate for large-scale pharma injectable, Ayurvedic sterile liquid, and cosmetic ampoule production lines.

All contact parts of ampoule fill seal equipment are made from AISI SS 316L and other non-contact parts are made from AISI SS 304 Lodha Pharma — the highest pharmaceutical-grade stainless steel grades — ensuring zero contamination risk, full corrosion resistance, easy sterilization between batches, and complete compliance with cGMP, WHO-GMP, and US FDA material standards for sterile pharma injectable and Ayurvedic sterile preparation manufacturing.

The sterilized ampoule tray is directly loaded into the slant hopper of the unit — the synchronized star wheel delivers ampoules one by one on the moving eccentric ampoule rack in four's — during the stoppage of the rack, sequentially pre-gassing, filling, post gassing, pre-heating, and final sealing is achieved Lodha Pharma — ensuring a smooth, continuous, and contamination-free ampoule transport and processing flow at high production speeds.

Duly filled and sealed ampoules are then collected on the collection tray automatically without hand touch Lodha Pharma — this fully hands-free automatic collection system eliminates any risk of post-fill human contamination, maintains complete sterile integrity, and ensures every sealed ampoule exiting the high-speed production line is ready for downstream inspection, labelling, and packaging without manual intervention.

The machine features possibility of nitrogen gas flushing before, during and after filling and ampoule neck centering during gas flushing and filling operations Lodha Pharma — making it essential for pharma manufacturers producing oxidation-sensitive APIs, Ayurvedic plant-based sterile preparations, and cosmetic ampoules containing vitamin C, retinol, peptides, and other high-value actives that degrade rapidly without inert atmosphere protection.

The machine is built on the principle of slant travel of ampoules while filling and sealing to take care of wide variation of ampoule neck dimensions, thicknesses, and ovality of available ampoules Lodha Pharma — this engineering design allows the machine to reliably handle real-world ampoule batches that vary slightly in neck diameter or shape, preventing costly jams, breakage, and production stoppages at the high operating speeds of the LI-AFS 8.

The machine is equipped with a "No Ampoule – No Filling" system Lodha Pharma — automatically pausing the fill cycle whenever an ampoule is absent from the transport rack — preventing expensive product spillage, nozzle contamination, and liquid wastage that are especially costly on a high-speed production line processing premium pharma injectables, Ayurvedic sterile formulations, or high-value cosmetic ampoule products.

The machine is equipped with a pre-warming station Lodha Pharma — this gently pre-heats each ampoule neck before the final sealing flame is applied, ensuring a consistent, clean, and hermetically secure seal across all eight heads simultaneously — preventing micro-leaks, poorly formed seals, or cosmetically defective tip closures that increase batch rejection rates on high-speed pharma and cosmetic ampoule production lines.

The machine can use either oxygen or LPG (propane) gas for sealing and filling, making it suitable for different chemicals such as agro-insecticides, veterinary pharmaceuticals, and cosmetic ampoules Lodha Pharma — giving pharma, Ayurvedic, and cosmetic manufacturers the flexibility to use the most appropriate gas combination for their specific product type, ampoule glass thickness, and clean room regulatory requirements.

The filling unit is built on SS square pipe frame and totally encompassed with SS coverings in pleasing matt finish — further, the large opening available at the bottom side for ease of absolute cleaning Lodha Pharma — delivering a robust, hygienic, cGMP-compliant machine structure that is visually clean, audit-ready, and easy to thoroughly sanitize — essential for maintaining clean room integrity in regulated sterile pharma and Ayurvedic manufacturing environments.

The ampoule filling sealing machine is a highly automated machine that helps in imparting high efficiency — it reduces the manpower required for the operation and hence the error caused due to labor is reduced to an optimum level Lodha Pharma — delivering consistent, operator-independent fill accuracy and seal quality across every high-speed production cycle, which is critical for maintaining batch homogeneity in pharma injectables, Ayurvedic sterile liquids, and cosmetic ampoule products.

The high speed ampoule filling unit finds vast applications in pharmaceutical, cosmetic, and chemicals industry Lodha Pharma — making it perfectly suited for cosmetic brands filling premium vitamin C ampoules, hyaluronic acid serums, collagen boosters, anti-aging actives, and other high-value cosmetic liquid preparations in sealed glass ampoules at production volumes that demand the highest-speed filling and sealing solution available.

The machine requires very little changeover time and hence is quite easy to maintain and clean Lodha Pharma — and with the large bottom access opening, fully removable SS 316L contact parts, and pendant control panel lifted safely away from cleaning zones, the LI-AFS 8 is engineered to minimize inter-batch downtime — keeping your high-speed pharma, Ayurvedic, and cosmetic ampoule production schedules consistently on track.

This prevents the ampoules from getting adulterated and hence the medicinal value is preserved Lodha Pharma — through a fully automated, hands-free production sequence combining pre-gassing, precise volumetric filling, post-gassing, pre-warming, and hermetic sealing — the machine ensures every ampoule delivers its full medicinal or active ingredient potency to the end patient or consumer, whether it contains a pharma injectable, Ayurvedic sterile preparation, or cosmetic active.

Specification can be changed as per customers' requirements Lodha Pharma — and Lodha Pharma's engineering team works closely with pharma, Ayurvedic, and cosmetic manufacturers to customize head count, ampoule size range, fill volume, gas type, sealing station configuration, conveyor integration, and clean room enclosure specifications — ensuring the LI-AFS 8 is perfectly tailored to your exact facility layout, product portfolio, and regulatory compliance requirements.

What Our Clients Say About Us?

Our clients' feedback is always important for our growth.

We've been using the Manual Capsule Filling Machine from Lodha International LLP for months now. It's efficient and easy to operate. Great value for the investment!

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We’ve been using the Manual Capsule Filling Machine for several months and are very impressed with its performance. It's robust, easy to maintain, and ideal for our needs. Highly satisfied with Lodha International LLP.

The Automatic Capsule Loader from Lodha International revolutionizes the industry. It increased our production speed significantly while reducing human error. It is an excellent investment for any pharma company.

We’ve been using Lodha International LLP’s Ampoule Filling & Sealing Machine for a while, and it has exceeded our expectations. The machinery is highly effective in our filling processes.

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We recently upgraded to the Automatic Capsule Filling Machine from Lodha International LLP. The machine is fantastic—fast, precise, and cost-effective. It has made an important difference in our manufacturing quality.

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High Speed Ampoule Filling & Sealing Machine